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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
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DC activated via dectin-1 convert Treg into IL-17 producers
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Retinoic Acid Enhances Foxp3 Induction Indirectly by Relieving Inhibition from CD4+CD44hi Cells
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Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
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In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells
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Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression
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TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
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T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
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Vitamin a metabolites induce gut-homing FoxP3+ regulatory T cells
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DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3+ conventional T cells
Udo Baron et al.
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Expression of ectonucleotidase CD39 by Foxp3+ Treg cells:: hydrolysis of extracellular ATP and immune suppression
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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β- and retinoic acid-dependent mechanism
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Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
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Hyoung-Pyo Kim et al.
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Altered activation of AKT is required for the suppressive function of human CD4+ CD25+ T regulatory cells
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Epigenetic control of the foxp3 locus in regulatory T cells
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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
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