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Tofacitinib Suppresses Antibody Responses to Protein Therapeutics in Murine Hosts
Masanori Onda et al.
JOURNAL OF IMMUNOLOGY (2014)
Inhibition of TYK2 and JAK1 Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis by Inhibiting IL-22 and the IL-23/IL-17 Axis
Melissa G. Works et al.
JOURNAL OF IMMUNOLOGY (2014)
Reversal of CD8 T-Cell-Mediated Mucocutaneous Graft-Versus-Host-Like Disease by the JAK Inhibitor Tofacitinib
Naoko Okiyama et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)
Systemic lupus erythematosus
Larissa Lisnevskaia et al.
LANCET (2014)
Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition
Luzhou Xing et al.
NATURE MEDICINE (2014)
Remission of Recalcitrant Dermatomyositis Treated with Ruxolitinib
Thorsten Hornung et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Potential pathogenetic role of Th17, Th0, and Th2 cells in erosive and reticular oral lichen planus
M-P Piccinni et al.
ORAL DISEASES (2014)
CXCL10 Is Critical for the Progression and Maintenance of Depigmentation in a Mouse Model of Vitiligo
Mehdi Rashighi et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Herpes Zoster and Tofacitinib Therapy in Patients With Rheumatoid Arthritis
Kevin L. Winthrop et al.
ARTHRITIS & RHEUMATOLOGY (2014)
Diagnosis and Treatment of Lichen Sclerosus An Update
Susanna K. Fistarol et al.
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY (2013)
A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis
W. C. Ports et al.
BRITISH JOURNAL OF DERMATOLOGY (2013)
Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesis
M-C. Lu et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2013)
Cutting Edge: STAT1 Is Required for IL-6-Mediated Bcl6 Induction for Early Follicular Helper Cell Differentiation
Youn Soo Choi et al.
JOURNAL OF IMMUNOLOGY (2013)
Immunoexpression of Interleukin-22 and Interleukin-23 in Oral and Cutaneous Lichen Planus Lesions: A Preliminary Study
Jun Chen et al.
MEDIATORS OF INFLAMMATION (2013)
Effects of the Janus Kinase Inhibitor CP-690550 (Tofacitinib) in a Rat Model of Oxazolone-Induced Chronic Dermatitis
Yasutomo Fujii et al.
PHARMACOLOGY (2013)
Drug Delivery with Topically Applied Nanoparticles: Science Fiction or Reality?
J. Lademann et al.
SKIN PHARMACOLOGY AND PHYSIOLOGY (2013)
IFNγR signaling mediates alloreactive T-cell trafficking and GVHD
Jaebok Choi et al.
BLOOD (2012)
Functional STAT3 deficiency compromises the generation of human T follicular helper cells
Cindy S. Ma et al.
BLOOD (2012)
Possible role of interleukin-17 in the pathogenesis of lichen planus
O. Shaker et al.
BRITISH JOURNAL OF DERMATOLOGY (2012)
A Mouse Model of Vitiligo with Focused Epidermal Depigmentation Requires IFN-γ for Autoreactive CD8+ T-Cell Accumulation in the Skin
John E. Harris et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
An Autoimmune Phenotype in Vulvar Lichen Sclerosus and Lichen Planus: A Th1 Response and High Levels of MicroRNA-155
Annelinde Terlou et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Graft-versus-host disease Part I. Pathogenesis and clinical manifestations of graft-versus-host disease
Sharon R. Hymes et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2012)
Preliminary clinical activity of a topical JAK1/2 inhibitor in the treatment of psoriasis
Naresh Punwani et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2012)
Medical Progress Alopecia Areata
Amos Gilhar et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Tofacitinib or Adalimumab versus Placebo in Rheumatoid Arthritis
Ronald F. van Vollenhoven et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Lichen Planus
Laurence Le Cleach et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Tofacitinib (CP-690,550), a Janus Kinase Inhibitor for Dry Eye Disease
Shiao Hui (Melissa) Liew et al.
OPHTHALMOLOGY (2012)
Deficiency of IL-22 Contributes to a Chronic Inflammatory Disease: Pathogenetic Mechanisms in Acne Inversa
Kerstin Wolk et al.
JOURNAL OF IMMUNOLOGY (2011)
Involvement of Tyrosine Kinase-2 in Both the IL-12/Th1 and IL-23/Th17 Axes In Vivo
Masayuki Ishizaki et al.
JOURNAL OF IMMUNOLOGY (2011)
Depletion of Autoreactive Plasma Cells and Treatment of Lupus Nephritis in Mice Using CEP-33779, a Novel, Orally Active, Selective Inhibitor of JAK2
Lily D. Lu et al.
JOURNAL OF IMMUNOLOGY (2011)
Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)
Kamran Ghoreschi et al.
JOURNAL OF IMMUNOLOGY (2011)
Comorbidity profiles among patients with alopecia areata: The importance of onset age, a nationwide population-based study
Szu-Ying Chu et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2011)
The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures
S. M. MCHUGH et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
Lynn Petukhova et al.
NATURE (2010)
Genetic susceptibility to systemic lupus erythematosus in the genomic era
Yun Deng et al.
NATURE REVIEWS RHEUMATOLOGY (2010)
γ-Secretase Gene Mutations in Familial Acne Inversa
Baoxi Wang et al.
SCIENCE (2010)
Activation of the Interferon-γ Signaling Pathway in Systemic Lupus Erythematosus Peripheral Blood Mononuclear Cells
Thomas Karonitsch et al.
ARTHRITIS AND RHEUMATISM (2009)
Janus kinases in immune cell signaling
Kamran Ghoreschi et al.
IMMUNOLOGICAL REVIEWS (2009)
History of atopy or autoimmunity increases risk of alopecia areata
Nazila Barahmani et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2009)
Selectivity and therapeutic inhibition of kinases: to be or not to be?
Kamran Ghoreschi et al.
NATURE IMMUNOLOGY (2009)
Vitiligo
Alain Taieb et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
PUVA-bath photochemotherapy and isotretinoin in sclerodermatous graft-versus-host disease
Kamran Ghoreschi et al.
EUROPEAN JOURNAL OF DERMATOLOGY (2008)
IL-33 can promote survival, adhesion and cytokine production in human mast cells
Motoyasu Iikura et al.
LABORATORY INVESTIGATION (2007)
Oral biopsies from patients with orofacial granulomatosis with histology resembling Crohn's disease have a prominent Th1 environment
Jona Freysdottir et al.
INFLAMMATORY BOWEL DISEASES (2007)
Activation of the STAT1 signalling pathway in lupus nephritis in MRL/lpr mice
J. Dong et al.
LUPUS (2007)
Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
Yoshiyuki Minegishi et al.
IMMUNITY (2006)
Type I interferon-associated cytotoxic inflammation in lichen planus
Joerg Wenzel et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2006)
Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history
C. Goh et al.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2006)
STAT4 deficiency reduces autoantibody production and glomerulonephritis in a mouse model of lupus
Zhiwei Xu et al.
CLINICAL IMMUNOLOGY (2006)
Clindamycin and rifampicin combination therapy for hidradenitis suppurativa
CO Mendonça et al.
BRITISH JOURNAL OF DERMATOLOGY (2006)
Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease
E Zorn et al.
BLOOD (2005)
Interferon-α/β-mediated innate immune mechanisms in dermatomyositis
SA Greenberg et al.
ANNALS OF NEUROLOGY (2005)
Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs
M Pesu et al.
IMMUNOLOGICAL REVIEWS (2005)
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
S Sano et al.
NATURE MEDICINE (2005)
Topical tacrolimus therapy for vitiligio: Therapeutic responses and skin messenger RNA expression of proinflammatory cytokines
PE Grimes et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2004)
Relation of an interleukin-10 promoter polymorphism to graft-versus-host disease and survival after hematopoietic cell transplantation
M Lin et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Immunopolarization of CD4+ and CD8+ T cells to type-1-like is associated with melanocyte loss in human vitiligo
A Wankowicz-Kalinska et al.
LABORATORY INVESTIGATION (2003)
Successful treatment of granulomatous cheilitis with thalidomide
P Thomas et al.
ARCHIVES OF DERMATOLOGY (2003)
Molecular profiles of inflammatory myopathies
SA Greenberg et al.
NEUROLOGY (2002)
Interferon-γ and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation
J Cavet et al.
BLOOD (2001)
Partial impairment of cytokine responses in Tyk2-deficient mice
M Karaghiosoff et al.
IMMUNITY (2000)