4.4 Article

A new mouse line with reduced GluA2 Q/R site RNA editing exhibits loss of dendritic spines, hippocampal CA1-neuron loss, learning and memory impairments and NMDA receptor-independent seizure vulnerability

Related references

Note: Only part of the references are listed.
Review Clinical Neurology

Novel drugs and early polypharmacotherapy in status epilepticus

Marta Amengual-Gual et al.

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY (2019)

Article Biochemistry & Molecular Biology

Inosine induces context-dependent recoding and translational stalling

Konstantin Licht et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Genetics & Heredity

A-to-I RNA editing - immune protector and transcriptome diversifier

Eli Eisenberg et al.

NATURE REVIEWS GENETICS (2018)

Review Neurosciences

The Good and the Bad of Glutamate Receptor RNA Editing

Alice Filippini et al.

MOLECULAR NEUROBIOLOGY (2017)

Article Biochemistry & Molecular Biology

RNA editing enzyme ADAR2 is a mediator of neuropathic pain after peripheral nerve injury

Hitoshi Uchida et al.

FASEB JOURNAL (2017)

Review Genetics & Heredity

ADAR RNA editing in human disease; more to it than meets the I

Angela Gallo et al.

HUMAN GENETICS (2017)

Article Biochemistry & Molecular Biology

Single-cell transcriptomics reveals specific RNA editing signatures in the human brain

Ernesto Picardi et al.

Review Genetics & Heredity

The evolution and adaptation of A-to-I RNA editing

Arielle L. Yablonovitch et al.

PLOS GENETICS (2017)

Article Neurosciences

Different Forms of AMPA Receptor Mediated LTP and Their Correlation to the Spatial Working Memory Formation

Derya R. Shimshek et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)

Article Biotechnology & Applied Microbiology

Editing inducer elements increases A-to-I editing efficiency in the mammalian transcriptome

Chammiran Daniel et al.

GENOME BIOLOGY (2017)

Article Biochemistry & Molecular Biology

Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease

Khen Khermesh et al.

Article Biochemistry & Molecular Biology

ADAR2-dependent GluA2 editing regulates cocaine seeking

H. D. Schmidt et al.

MOLECULAR PSYCHIATRY (2015)

Article Geriatrics & Gerontology

Hippocampus-specific deficiency in RNA editing of GluA2 in Alzheimer's disease

Inna Gaisler-Salomon et al.

NEUROBIOLOGY OF AGING (2014)

Article Biology

Incorporation of inwardly rectifying AMPA receptors at silent synapses during hippocampal long-term potentiation

Daiju Morita et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Article Multidisciplinary Sciences

LTP requires a reserve pool of glutamate receptors independent of subunit type

Adam J. Granger et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing

Andrew C. Penn et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Biochemistry & Molecular Biology

Requirement of the RNA-editing Enzyme ADAR2 for Normal Physiology in Mice

Marion Horsch et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Biochemistry & Molecular Biology

Functions and Regulation of RNA Editing by ADAR Deaminases

Kazuko Nishikura

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)

Article Neurosciences

Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2

Takuto Hideyama et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Multidisciplinary Sciences

A Role for Calcium-Permeable AMPA Receptors in Synaptic Plasticity and Learning

Brian J. Wiltgen et al.

PLOS ONE (2010)

Review Pharmacology & Pharmacy

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

Stephen F. Traynelis et al.

PHARMACOLOGICAL REVIEWS (2010)

Article Neurosciences

Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures

Sanjay N. Rakhade et al.

JOURNAL OF NEUROSCIENCE (2008)

Article Multidisciplinary Sciences

Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving

Kelly L. Conrad et al.

NATURE (2008)

Article Pharmacology & Pharmacy

Two mechanisms of action of the adamantane derivative IEM-1460 at human AMPA-type glutamate receptors

F Schlesinger et al.

BRITISH JOURNAL OF PHARMACOLOGY (2005)

Article Neurosciences

A genetic switch for epilepsy in adult mice

HE Krestel et al.

JOURNAL OF NEUROSCIENCE (2004)

Article Neurosciences

AMPA receptor tetramerization is mediated by Q/R editing

IH Greger et al.

NEURON (2003)

Article Clinical Neurology

GluR2(B) knockdown accelerates CA3 injury after kainate seizures

LK Friedman et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)

Article Multidisciplinary Sciences

Ischemic preconditioning acts upstream of GluR2 down-regulation to afford neuroprotection in the hippocampal CA1

H Tanaka et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Multidisciplinary Sciences

Underediting of glutamate receptor GluR-B mRNA in malignant gliomas

S Maas et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)