Related references
Note: Only part of the references are listed.Soluble TREM2 and Inflammatory Proteins in Alzheimer's Disease Cerebrospinal Fluid
Boris-Stephan Rauchmann et al.
JOURNAL OF ALZHEIMERS DISEASE (2020)
The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer's disease
Hlin Kvartsberg et al.
ACTA NEUROPATHOLOGICA (2019)
When is Alzheimers not dementiauCochrane commentary on The National Institute on Ageing and Alzheimers Association Research Framework for Alzheimers Disease
Jenny McCleery et al.
AGE AND AGEING (2019)
Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers
Cristian C. Constantinescu et al.
MOLECULAR IMAGING AND BIOLOGY (2019)
Lowering of Amyloid-Beta by β-Secretase Inhibitors - Some Informative Failures
David S. Knopman
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease A Randomized Clinical Trial
Christopher H. van Dyck et al.
JAMA NEUROLOGY (2019)
Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease
Sebastian Palmqvist et al.
EMBO MOLECULAR MEDICINE (2019)
Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates
Songye Li et al.
ACS CHEMICAL NEUROSCIENCE (2019)
Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology
Asa Sandelius et al.
ALZHEIMERS & DEMENTIA (2019)
Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
Emma Nichols et al.
LANCET NEUROLOGY (2019)
Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid
Alberto Lleo et al.
MOLECULAR & CELLULAR PROTEOMICS (2019)
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
Hongjun Fu et al.
NATURE NEUROSCIENCE (2019)
Beyond the neuron-cellular interactions early in Alzheimer disease pathogenesis
Christopher M. Henstridge et al.
NATURE REVIEWS NEUROSCIENCE (2019)
EEG time signature in Alzheimer's disease: Functional brain networks falling apart
Una Smailovic et al.
NEUROIMAGE-CLINICAL (2019)
Cognition comes of age: comments on the new FDA draft guidance for early Alzheimer's disease
John E. Harrison
ALZHEIMERS RESEARCH & THERAPY (2018)
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology
Erik Portelius et al.
ACTA NEUROPATHOLOGICA (2018)
NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
Clifford R. Jack et al.
ALZHEIMERS & DEMENTIA (2018)
Anti-Amyloid-β Monoclonal Antibodies for Alzheimer's Disease: Pitfalls and Promise
Christopher H. van Dyck
BIOLOGICAL PSYCHIATRY (2018)
Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach
Erika Bereczki et al.
BRAIN (2018)
Molecular biomarkers of Alzheimer's disease: progress and prospects
Tammaryn Lashley et al.
DISEASE MODELS & MECHANISMS (2018)
The Amyloid-beta Oligomer Hypothesis: Beginning of the Third Decade
Erika N. Cline et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Quantitative EEG power and synchronization correlate with Alzheimer's disease CSF biomarkers
Una Smailovic et al.
NEUROBIOLOGY OF AGING (2018)
Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau
Joseph McInnes et al.
NEURON (2018)
Prospects for strain-specific immunotherapy in Alzheimer's disease and tauopathies
Alice Bittar et al.
NPJ VACCINES (2018)
Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer's disease
Eleanor K. Pickett et al.
ACTA NEUROPATHOLOGICA (2018)
Soluble tau aggregates, not large fibrils, are the toxic species that display seeding and cross-seeding behavior
Gaurav Ghag et al.
PROTEIN SCIENCE (2018)
Complementing Tau: New Data Show that the Complement System Is Involved in Degeneration in Tauopathies
Caitlin Davies et al.
NEURON (2018)
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
Borislav Dejanovic et al.
NEURON (2018)
Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease
Alexandra Litvinchuk et al.
NEURON (2018)
Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex
Aladdin Riad et al.
SCIENTIFIC REPORTS (2018)
Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer's disease: results of a randomized, double-blind, placebo-controlled phase 2a study
Philip Scheltens et al.
ALZHEIMERS RESEARCH & THERAPY (2018)
Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapses
Yang Yu et al.
LIFE SCIENCE ALLIANCE (2018)
Binding Sites for Amyloid-β Oligomers and Synaptic Toxicity
Levi M. Smith et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Therapeutics of Neurotransmitters in Alzheimer's Disease
Ramesh Kandimalla et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP
Zemin Wang et al.
JOURNAL OF NEUROSCIENCE (2017)
EEG spectral analysis as a putative early prognostic biomarker in nondemented, amyloid positive subjects
Alida A. Gouw et al.
NEUROBIOLOGY OF AGING (2017)
Distinct phenotypes of three-repeat and four-repeat human tau in a transgenic model of tauopathy
Megan A. Sealey et al.
NEUROBIOLOGY OF DISEASE (2017)
Identification of the gene that codes for the σ2 receptor
Assaf Alon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice
Qiaoqiao Shi et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Tau association with synaptic vesicles causes presynaptic dysfunction
Lujia Zhou et al.
NATURE COMMUNICATIONS (2017)
APP mouse models for Alzheimer's disease preclinical studies
Hiroki Sasaguri et al.
EMBO JOURNAL (2017)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Hadas Keren-Shaul et al.
CELL (2017)
Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease
Laura T. Haas et al.
BRAIN (2016)
Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status
Laura Piccio et al.
ACTA NEUROPATHOLOGICA (2016)
Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia
Erika Bereczki et al.
ALZHEIMERS & DEMENTIA (2016)
Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability
Martijn C. de Wilde et al.
ALZHEIMERS & DEMENTIA (2016)
The amyloid hypothesis of Alzheimer's disease at 25years
Dennis J. Selkoe et al.
EMBO MOLECULAR MEDICINE (2016)
sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers
Marc Suarez-Calvet et al.
EMBO MOLECULAR MEDICINE (2016)
Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease
Rosemary J. Jackson et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2016)
Non-Fibrillar Oligomeric Amyloid-beta within Synapses
Eleanor K. Pickett et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease
Amanda Heslegrave et al.
MOLECULAR NEURODEGENERATION (2016)
Increased CSF neurogranin concentration is specific to Alzheimer disease
Henrietta Wellington et al.
NEUROLOGY (2016)
Imaging synaptic density in the living human brain
Sjoerd J. Finnema et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Diagnostic and Prognostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease
Rawan Tarawneh et al.
JAMA NEUROLOGY (2016)
Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis
Kirsten L. Viola et al.
ACTA NEUROPATHOLOGICA (2015)
Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease
Hlin Kvartsberg et al.
ALZHEIMERS & DEMENTIA (2015)
Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer's disease
Erik Portelius et al.
BRAIN (2015)
Pathological Tau Disrupts Ongoing Network Activity
Noa Menkes-Caspi et al.
NEURON (2015)
Synaptic Change in the Posterior Cingulate Gyrus in the Progression of Alzheimer's Disease
Stephen W. Scheff et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease
Ann Brinkmalm et al.
MOLECULAR NEURODEGENERATION (2014)
Single App knock-in mouse models of Alzheimer's disease
Takashi Saito et al.
NATURE NEUROSCIENCE (2014)
Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment
David R. Whitfield et al.
NEUROBIOLOGY OF AGING (2014)
The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer's Disease
Tara L. Spires-Jones et al.
NEURON (2014)
The Effect of Souvenaid on Functional Brain Network Organisation in Patients with Mild Alzheimer's Disease: A Randomised Controlled Study
Hanneke de Waal et al.
PLOS ONE (2014)
Alzheimer's Therapeutics Targeting Amyloid Beta 1-42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity
Nicholas J. Izzo et al.
PLOS ONE (2014)
Alzheimer's Therapeutics Targeting Amyloid Beta 1-42 Oligomers I: Abeta 42 Oligomer Binding to Specific Neuronal Receptors Is Displaced by Drug Candidates That Improve Cognitive Deficits
Nicholas J. Izzo et al.
PLOS ONE (2014)
The synaptic plasticity and memory hypothesis: encoding, storage and persistence
Tomonori Takeuchi et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
Eyes-closed task-free electroencephalography in clinical trials for Alzheimer’s disease: an emerging method based upon brain dynamics
Elisabeth CW van Straaten et al.
Alzheimers Research & Therapy (2014)
The identification of mitochondrial DNA variants in glioblastoma multiforme
Ka Yu Yeung et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Amyloid-Beta Oligomerization in Alzheimer Dementia versus High-Pathology Controls
Thomas J. Esparza et al.
ANNALS OF NEUROLOGY (2013)
Brain amyloid-β oligomers in ageing and Alzheimer's disease
Sylvain E. Lesne et al.
BRAIN (2013)
Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology
Beatriz G. Perez-Nievas et al.
BRAIN (2013)
Effects of acetylcholinesterase inhibitors and memantine on resting-state electroencephalographic rhythms in Alzheimer's disease patients
Claudio Babiloni et al.
CLINICAL NEUROPHYSIOLOGY (2013)
Synapse Stability in the Precuneus Early in the Progression of Alzheimer's Disease
Stephen W. Scheff et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Promiscuous Alzheimer's Amyloid: Yet Another Partner
Iryna Benilova et al.
SCIENCE (2013)
Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain
Eloise Hudry et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
Bradley T. Hyman et al.
ALZHEIMERS & DEMENTIA (2012)
The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System
Hwan-Ching Tai et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β
Robert M. Koffie et al.
BRAIN (2012)
Efficacy of Souvenaid in Mild Alzheimer's Disease: Results from a Randomized, Controlled Trial
Philip Scheltens et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
Peter T. Nelson et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2012)
Different β-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity
Fuxiang Bao et al.
NEUROBIOLOGY OF AGING (2012)
Soluble forms of tau are toxic in Alzheimer's disease
Katherine J. Kopeikina et al.
TRANSLATIONAL NEUROSCIENCE (2012)
Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy
Johanna L. Crimins et al.
ACTA NEUROPATHOLOGICA (2011)
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Reisa A. Sperling et al.
ALZHEIMERS & DEMENTIA (2011)
Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain
Katherine J. Kopeikina et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Reversibility of Tau-Related Cognitive Defects in a Regulatable FTD Mouse Model
Astrid Sydow et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2011)
Tau Protein Is Required for Amyloid β-Induced Impairment of Hippocampal Long-Term Potentiation
Olivia A. Shipton et al.
JOURNAL OF NEUROSCIENCE (2011)
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
Astrid Sydow et al.
JOURNAL OF NEUROSCIENCE (2011)
Amyloid-β/Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease
Erik D. Roberson et al.
JOURNAL OF NEUROSCIENCE (2011)
Reversing EphB2 depletion rescues cognitive functions in Alzheimer model
Moustapha Cisse et al.
NATURE (2011)
Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI
Susan M. Landau et al.
NEUROBIOLOGY OF AGING (2011)
Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site
Jinbin Xu et al.
NATURE COMMUNICATIONS (2011)
Neuropathological Alterations in Alzheimer Disease
Alberto Serrano-Pozo et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)
Disease progression meta-analysis model in Alzheimer's disease
Kaori Ito et al.
ALZHEIMERS & DEMENTIA (2010)
The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core
William J. Jagust et al.
ALZHEIMERS & DEMENTIA (2010)
Neurogranin in cerebrospinal fluid as a marker of synaptic degeneration in Alzheimer's disease
Annika Thorsell et al.
BRAIN RESEARCH (2010)
Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
Lars M. Ittner et al.
CELL (2010)
Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs
A. B. Rocher et al.
EXPERIMENTAL NEUROLOGY (2010)
Probing the Biology of Alzheimer's Disease in Mice
Karen H. Ashe et al.
NEURON (2010)
Changes in cognitive domains during three years in patients with Alzheimer's disease treated with donepezil
Cecilia M. Persson et al.
BMC NEUROLOGY (2009)
Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology
Manuela Polydoro et al.
JOURNAL OF NEUROSCIENCE (2009)
Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease
Tara L. Spires Jones et al.
NEUROBIOLOGY OF DISEASE (2009)
Oligomeric amyloid β associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
Robert M. Koffie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice
Kishore V. Kuchibhotla et al.
SCIENCE (2009)
Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease
Lisa Mosconi et al.
MITOCHONDRIA AND OXIDATIVE STRESS IN NEURODEGENERATIVE DISORDERS (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease
Alireza Kashani et al.
NEUROBIOLOGY OF AGING (2008)
Rivastigmine effects on EEG spectra and three-dimensional LORETA functional imaging in Alzheimer's disease
Lorena R. R. Gianotti et al.
PSYCHOPHARMACOLOGY (2008)
Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
Marc Aurel Busche et al.
SCIENCE (2008)
Rapid, concurrent alterations in pre- and postsynaptic structure induced by naturally-secreted amyloid-β protein
Barbara Calabrese et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
Erik D. Roberson et al.
SCIENCE (2007)
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
Yasumasa Yoshiyama et al.
NEURON (2007)
Aβ oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
Pascale N. Lacor et al.
JOURNAL OF NEUROSCIENCE (2007)
Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy
TL Spires et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
A specific amyloid-β protein assembly in the brain impairs memory
S Lesné et al.
NATURE (2006)
Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy
TL Spires et al.
JOURNAL OF NEUROSCIENCE (2005)
Tau suppression in a neurodegenerative mouse model improves memory function
K SantaCruz et al.
SCIENCE (2005)
Natural oligomers of the amyloid-protein specifically disrupt cognitive function
JP Cleary et al.
NATURE NEUROSCIENCE (2005)
EEG dynamics in patients with Alzheimer's disease
JS Jeong
CLINICAL NEUROPHYSIOLOGY (2004)
Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies
SW Scheff et al.
NEUROBIOLOGY OF AGING (2003)
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
DM Walsh et al.
NATURE (2002)
Neuroscience - The molecular biology of memory storage: A dialogue between genes and synapses
ER Kandel
SCIENCE (2001)
Short-term rivastigmine treatment reduces EEG slow-wave power in Alzheimer patients
G Adler et al.
NEUROPSYCHOBIOLOGY (2001)
Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
C Janus et al.
NATURE (2000)
Share Paper
