Journal
WORLD NEUROSURGERY
Volume 134, Issue -, Pages 337-342Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.wneu.2019.11.019
Keywords
Meningioma; Rhabdoid papillary lesion; Stereotactic radiosurgery; Surgery; TERT
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BACKGROUND: In the management of meningiomas, single-fraction stereotactic radiosurgery (SRS) is an established alternative treatment to surgical resection. However, its effects on tumorigenesis and malignant transformation are still uncertain. CASE DESCRIPTION: We have described a grade II parafalcine meningioma was initially surgically resected (Simpson 2 clearance) and then managed with a single dose of SRS on recurrence. The tumor recurred again 7 years later, with histological features of a grade III rhabdoid-papillary lesion, with local brain invasion. CONCLUSION: To the best of our knowledge, this is the first report to describe malignant transformation of a grade II to grade III meningioma after SRS to date.
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