Related references
Note: Only part of the references are listed.The impact of the rs8005161 polymorphism on G protein-coupled receptor GPR65 (TDAG8) pH-associated activation in intestinal inflammation
Irina V. Tcymbarevich et al.
BMC GASTROENTEROLOGY (2019)
Lack of the pH-sensing Receptor TDAG8 [GPR65] in Macrophages Plays a Detrimental Role in Murine Models of Inflammatory Bowel Disease
Irina Tcymbarevich et al.
JOURNAL OF CROHNS & COLITIS (2019)
The Proton-activated Receptor GPR4 Modulates Intestinal Inflammation
Yu Wang et al.
JOURNAL OF CROHNS & COLITIS (2018)
Calcium signaling at the endoplasmic reticulum: fine-tuning stress responses
Amado Carreras-Sureda et al.
CELL CALCIUM (2018)
Cellular Stress Responses and Gut Microbiota in Inflammatory Bowel Disease
Siyan Stewart Cao
GASTROENTEROLOGY RESEARCH AND PRACTICE (2018)
Intestinal Activation of pH-Sensing Receptor OGR1 [GPR68] Contributes to Fibrogenesis
Senta Hutter et al.
JOURNAL OF CROHNS & COLITIS (2018)
Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells
Lixue Dong et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Functional expression of calcium-permeable canonical transient receptor potential 4-containing channels promotes migration of medulloblastoma cells
Wei-Chun Wei et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Intestinal Epithelial Cell Endoplasmic Reticulum Stress and Inflammatory Bowel Disease Pathogenesis: An Update Review
Xiaoshi Ma et al.
FRONTIERS IN IMMUNOLOGY (2017)
GPR4 deficiency alleviates intestinal inflammation in a mouse model of acute experimental colitis
Edward J. Sanderlin et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk
Kara G. Lassen et al.
IMMUNITY (2016)
An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response
Max Brown et al.
JOURNAL OF CELL SCIENCE (2016)
Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68)
Cheryl de Valliere et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2016)
The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment
Cheryl de Valliere et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2015)
G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation
Cheryl de Valliere et al.
INFLAMMATORY BOWEL DISEASES (2015)
Endoplasmic Reticulum Stress and Unfolded Protein Response in Inflammatory Bowel Disease
Stewart S. Cao
INFLAMMATORY BOWEL DISEASES (2015)
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Jimmy Z. Liu et al.
NATURE GENETICS (2015)
Endoplasmic Reticulum Stress in Intestinal Epithelial Cell Function and Inflammatory Bowel Disease
Katherine Luo et al.
GASTROENTEROLOGY RESEARCH AND PRACTICE (2015)
Emerging roles for the pH-sensing G protein-coupled receptors in response to acidotic stress
Edward J. Sanderlin et al.
CELL HEALTH AND CYTOSKELETON (2015)
Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells
Ahmed A. Ashour et al.
APOPTOSIS (2014)
被撤回的出版物: Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells (Retracted article. See vol. 48, 2021)
Xiu Cheng et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2014)
Ovarian Cancer G protein-Coupled Receptor 1 Is Involved in Acid-Induced Apoptosis of Endplate Chondrocytes in Intervertebral Discs
Feng-Lai Yuan et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
Glucose-Regulated Protein 78 ( Grp78) Confers Chemoresistance to Tumor Endothelial Cells under Acidic Stress
Fernanda Visioli et al.
PLOS ONE (2014)
Regulation of inflammation by extracellular acidification and proton-sensing GPCRs
Fumikazu Okajima
CELLULAR SIGNALLING (2013)
Acidosis Activation of the Proton-Sensing GPR4 Receptor Stimulates Vascular Endothelial Cell Inflammatory Responses Revealed by Transcriptome Analysis
Lixue Dong et al.
PLOS ONE (2013)
Regulated Expression of pH Sensing G Protein-Coupled Receptor-68 Identified through Chemical Biology Defines a New Drug Target for Ischemic Heart Disease
Jamie L. Russell et al.
ACS CHEMICAL BIOLOGY (2012)
Coupling Hippocampal Neurogenesis to Brain pH through Proneurogenic Small Molecules That Regulate Proton Sensing G Protein-Coupled Receptors
Jay W. Schneider et al.
ACS CHEMICAL NEUROSCIENCE (2012)
The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH
H. Saxena et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Xiaohu Tang et al.
CANCER RESEARCH (2012)
mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway
H. Kato et al.
CELL DEATH AND DIFFERENTIATION (2012)
The Proton-activated G Protein Coupled Receptor OGR1 Acutely Regulates the Activity of Epithelial Proton Transport Proteins
Nilufar Mohebbi et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2012)
Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice
Michael J. Jurczak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Activation of JNK/c-Jun is required for the proliferation, survival, and angiogenesis induced by EET in pulmonary artery endothelial cells
Jun Ma et al.
JOURNAL OF LIPID RESEARCH (2012)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins et al.
NATURE (2012)
NIH Image to ImageJ: 25 years of image analysis
Caroline A. Schneider et al.
NATURE METHODS (2012)
Acidic stressER stress axis for blunted activation of NF-B in mesothelial cells exposed to peritoneal dialysis fluid
Hisashi Johno et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2012)
Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor
Lorenza Wyder et al.
ANGIOGENESIS (2011)
Activation of T cell death-associated gene 8 attenuates inflammation by negatively regulating the function of inflammatory cells
Yoshiko Onozawa et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation
Chuan-Ming Xie et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
JNK regulates FoxO-dependent autophagy in neurons
Ping Xu et al.
GENES & DEVELOPMENT (2011)
c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells
Ting Sun et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Carl A. Anderson et al.
NATURE GENETICS (2011)
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
Marie Cargnello et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2011)
Extracellular acidification stimulates IL-6 production and Ca2+ mobilization through proton-sensing OGR1 receptors in human airway smooth muscle cells
Isao Ichimonji et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2010)
Protein kinase C inhibits autophagy and phosphorylates LC3
Houbo Jiang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis
Arthur Kaser et al.
CURRENT OPINION IN GASTROENTEROLOGY (2010)
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Andre Franke et al.
NATURE GENETICS (2010)
Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation
Chew Hooi Wong et al.
PLOS ONE (2010)
The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor
Yuichiro Ihara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
PKCδ signaling A dual role in regulating hypoxic stress-induced autophagy and apoptosis
Jo-Lin Chen et al.
AUTOPHAGY (2009)
Regulation of endothelin-1-induced interleukin-6 production by Ca2+ influx in human airway smooth muscle cells
Susumu Iwata et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy
Sophie Pattingre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Involvement of Proton-Sensing TDAG8 in Extracellular Acidification-Induced Inhibition of Proinflammatory Cytokine Production in Peritoneal Macrophages
Chihiro Mogi et al.
JOURNAL OF IMMUNOLOGY (2009)
Endoplasmic Reticulum Stress-Mediated Autophagy/Apoptosis Induced by Capsaicin (8-Methyl-N-vanillyl-6-nonenamide) and Dihydrocapsaicin is Regulated by the Extent of c-Jun NH2-Terminal Kinase/Extracellular Signal-Regulated Kinase Activation in WI38 Lung Epithelial Fibroblast Cells
Seon-Hee Oh et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome
Claudio Hetz et al.
MOLECULAR CELL (2009)
Abnormalities in Osteoclastogenesis and Decreased Tumorigenesis in Mice Deficient for Ovarian Cancer G Protein-Coupled Receptor 1
Hui Li et al.
PLOS ONE (2009)
Extracellular acidification enhances osteoclast survival through an NFAT-independent, protein kinase C-dependent pathway
Alexey Pereverzev et al.
BONE (2008)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
Extracellular acidification elicits spatially and temporally distinct Ca2+ signals
Wan-Chen Huang et al.
CURRENT BIOLOGY (2008)
From endoplasmic-reticulum stress to the inflammatory response
Kezhong Zhang et al.
NATURE (2008)
Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer
Lisam Shanjukumar Singh et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
PKCδ and tissue transglutarninase in pancreatic cancer cells are novel inhibitors of autophagy
Bulent Ozpolat et al.
AUTOPHAGY (2007)
Autophagy is activated for cell survival after endoplasmic reticulum stress
Maiko Ogata et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Insulin-like growth factor-1 and TNF-α regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells
Guanghong Jia et al.
IMMUNOLOGY AND CELL BIOLOGY (2006)
The JNK are important for development and survival of macrophages
SR Himes et al.
JOURNAL OF IMMUNOLOGY (2006)
Review - Receptors for protons or lipid messengers or both?
Klaus Seuwen et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2006)
c-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells
M Gururajan et al.
BLOOD (2005)
Identification of T cell death-associated gene 8 ( TDAG8) as a novel acid sensing G-protein-coupled receptor
S Ishii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Acidosis causes endoplasmic reticulum stress and caspase-12-mediated astrocyte death
K Aoyama et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2005)
G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers
WC Sin et al.
ONCOGENE (2004)
Why do cancers have high aerobic glycolysis?
RA Gatenby et al.
NATURE REVIEWS CANCER (2004)
TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor
JQ Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Proton-sensing G-protein-coupled receptors
MG Ludwig et al.
NATURE (2003)
Bradykinin induces interleukin-6 production in human airway smooth muscle cells -: Modulation by Th2 cytokines and dexamethasone
CD Huang et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2003)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)
Determinants of blood pH in health and disease
JA Kellum
CRITICAL CARE (2000)
Endogenous airway acidification - Implications for asthma pathophysiology
JF Hunt et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)