Journal
DRUG DESIGN DEVELOPMENT AND THERAPY
Volume 14, Issue -, Pages 951-959Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/DDDT.S240615
Keywords
alopecia; androgenetic alopecia; dutasteride; hair loss; topical finasteride; therapy
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The currently approved treatment for female pattern hair loss (FPHL) includes topical minoxidil administration; however, this treatment fails to achieve hair regrowth in some patients. Finasteride, a selective 5 alpha-reductase inhibitor (5-ARI), may be considered as an alternative treatment. However, because of its potential teratogenic effects, clinical studies and use of finasteride for FPHL are limited. In this review, we aim to summarize the literature regarding the pharmacology, clinical efficacy, and adverse effects of oral finasteride for the treatment of FPHL and to provide novel therapeutic options including topical finasteride and dutasteride, a new generation 5-ARI, for the treatment of FPHL.
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