Journal
CANCER DISCOVERY
Volume 10, Issue 1, Pages 23-25Publisher
AMER ASSOC CANCER RESEARCH
DOI: 10.1158/2159-8290.CD-19-1261
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KRAS(G12R) mutations occur almost exclusively in pancreatic ductal adenocarcinoma. The results of a study that reveals specific differences in KRAS downstream signaling and metabolic rewiring of pancreatic cancer cells harboring KRAS(G12R) mutations promise to improve our possibilities to better stratify patients for individualized therapies.
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