4.3 Article

Walkability and its association with prevalent and incident diabetes among adults in different regions of Germany: results of pooled data from five German cohorts

Journal

BMC ENDOCRINE DISORDERS
Volume 20, Issue 1, Pages -

Publisher

BMC
DOI: 10.1186/s12902-019-0485-x

Keywords

Built environment; Walkability; Diabetes; Cardio-metabolic risk factors; Epidemiology

Funding

  1. Competence Network Diabetes Mellitus of the German Federal Ministry of Education and Research (BMBF) [01GI1110C]
  2. Competence Network Obesity (BMBF) [01GI1121B]
  3. Deutsche Forschungsgemeinschaft as part of the Collaborative Research Center 598 Heart failure in the elderly-cellular mechanisms and therapy at the Medical Faculty of the Martin-LutherUniversity Halle-Wittenberg
  4. Wilhelm-Roux Programme of the Martin-Luther-University Halle-Wittenberg
  5. Ministry of Education and Cultural Affairs of Saxony-Anhalt
  6. Federal Employment Office
  7. German Federal Ministry of Education and Research (BMBF) [01ZZ0403]
  8. Ministry for Education, Research, and Cultural Affairs
  9. Ministry for Social Affairs of the Federal State of Mecklenburg-West Pomerania
  10. Heinz Nixdorf Foundation (Germany)
  11. German Ministry of Education and Science
  12. Helmholtz Zentrum Munchen-German Research Center for Environmental Health - German Federal Ministry of Education and Research
  13. State of Bavaria
  14. Munich Center of Health Sciences (MCHealth), Ludwig-Maximilians-Universitat Munchen, as part of LMUinnovativ
  15. German Migraine and Headache Society
  16. Allmiral
  17. Astra-Zeneca
  18. BerlinChemie
  19. Boehringer Ingelheim Pharma
  20. Boots Healthcare
  21. GlaxoSmithKline
  22. Janssen Cilag
  23. McNeil Pharmaceuticals
  24. MSD Sharp Dohme
  25. Pfizer
  26. National Institute for Health Research (NIHR) Collaborations for Leadership in Applied Health Research and Care the West Midlands

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Background Highly walkable neighbourhoods may increase transport-related and leisure-time physical activity and thus decrease the risk for obesity and obesity-related diseases, such as type 2 diabetes (T2D). Methods We investigated the association between walkability and prevalent/incident T2D in a pooled sample from five German cohorts. Three walkability measures were assigned to participant's addresses: number of transit stations, points of interest, and impedance (restrictions to walking due to absence of intersections and physical barriers) within 640 m. We estimated associations between walkability and prevalent/incident T2D with modified Poisson regressions and adjusted for education, sex, age at baseline, and cohort. Results Of the baseline 16,008 participants, 1256 participants had prevalent T2D. Participants free from T2D at baseline were followed over a mean of 9.2 years (SD: 3.5, minimum: 1.6, maximum: 14.8 years). Of these, 1032 participants developed T2D. The three walkability measures were not associated with T2D. The estimates pointed toward a zero effect or were within 7% relative risk increase per 1 standard deviation with 95% confidence intervals including 1. Conclusion In the studied German settings, walkability differences might not explain differences in T2D.

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