Journal
BIOMEDICAL OPTICS EXPRESS
Volume 11, Issue 3, Pages 1298-1305Publisher
OPTICAL SOC AMER
DOI: 10.1364/BOE.383583
Keywords
-
Funding
- Ligue Contre le Cancer
- Agence Nationale de la Recherche
- Centre National d'Etudes Spatiales
- Infrastructure d'avenir en Biologie Sante [ANR11-INBS-0006]
Ask authors/readers for more resources
The early detection of microvascular changes in cancer diagnosis is needed in the clinic. A change in the vascular bifurcation density is a biomarker for the sprouting activity. Here, Optical-Resolution PhotoAcoustic Microscopy is used for quantitative vascular bifurcation mapping in 2D after the creation of Virtual Tubes out of Bifurcations. In stacks of OR-PAM images of the hemoglobin distribution, bifurcations become tubes and are selected by the 3D tubeness filter. These fast analyses will be compared to a classical approach and are easier to implement for functional analysis of the vascular bifurcation density in healthy and diseased tissues. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available