Journal
ACS CATALYSIS
Volume 10, Issue 5, Pages 3398-3403Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.9b05214
Keywords
amide; C-C activation; C-H activation; arylation; rhodium catalysis; DFT
Categories
Funding
- National Natural Science Foundation of China [21472128]
- Sichuan Science and Technology Program [2018JY560]
Ask authors/readers for more resources
A rhodium-catalyzed transarylation of benzamides via selective C-C bond activation with arylboronic acids was described, which was distinct from the conventional metal-catalyzed C-N bond activation. This transformation exhibited good functional group compatibility with yields up to 88%, offering a practical approach for the construction and functionalization of benzamides. Preliminary experimental and computational studies revealed the selectivity of metal insertion into the C-C bond or the C-N bond was greatly affected by substituents on the amide's N atom.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available