Zwitterionic 1,2,3-Triazolium Amidate as a Catalyst for Photoinduced Hydrogen-Atom Transfer Radical Alkylation

A zwitterionic 1,2,3-triazolium amidate was designed for use as an effective modular hydrogen-atom transfer catalyst for photoredox C-H functionalization. This zwitterionic amidate is stable yet amenable to single-electron oxidation for generating a highly reactive amidyl radical. In cooperation with an Ir-based visible-light photoredox catalyst, the optimal catalyst enables the efficient direct alkylation of the C-H bonds of various nitrogen-or oxygen-containing organic compounds.