Related references
Note: Only part of the references are listed.Cationic Polymer-Mediated CRISPR/Cas9 Plasmid Delivery for Genome Editing
Zhen Zhang et al.
MACROMOLECULAR RAPID COMMUNICATIONS (2019)
A boronic acid-rich dendrimer with robust and unprecedented efficiency for cytosolic protein delivery and CRISPR-Cas9 gene editing
Chongyi Liu et al.
SCIENCE ADVANCES (2019)
Tumor immune microenvironment and nano-immunotherapeutics in colorectal cancer
Yang Xiong et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2019)
Cytosolic delivery of CRISPR/Cas9 ribonucleoproteins for genome editing using chitosan-coated red fluorescent protein
Jie Qiao et al.
CHEMICAL COMMUNICATIONS (2019)
Nanoparticle-Mediated Trapping of Wnt Family Member 5A in Tumor Microenvironments Enhances Immunotherapy for B-Raf Proto-Oncogene Mutant Melanoma
Qi Liu et al.
ACS Nano (2018)
Nanocarrier-Mediated Chemo-Immunotherapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma
Qi Liu et al.
ACS NANO (2018)
Targeted drug delivery to melanoma
Qi Liu et al.
ADVANCED DRUG DELIVERY REVIEWS (2018)
Thermo-triggered Release of CRISPR-Cas9 System by Lipid-Encapsulated Gold Nanoparticles for Tumor Therapy
Peng Wang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Reduced Blood Lipid Levels With In Vivo CRISPR-Cas9 Base Editing of ANGPTL3
Alexandra C. Chadwick et al.
CIRCULATION (2018)
Effective PEI-mediated delivery of CRISPR-Cas9 complex for targeted gene therapy
Nari Ryu et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)
Engineering the Delivery System for CRISPR-Based Genome Editing
Zachary Glass et al.
TRENDS IN BIOTECHNOLOGY (2018)
A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
Jonathan D. Finn et al.
CELL REPORTS (2018)
Systemic delivery of CRISPR/Cas9 with PEG-PLGA nanoparticles for chronic myeloid leukemia targeted therapy
Yang Liu et al.
BIOMATERIALS SCIENCE (2018)
Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours
Bumwhee Lee et al.
NATURE BIOMEDICAL ENGINEERING (2018)
PEGylated Chitosan for Nonviral Aerosol and Mucosal Delivery of the CRISPR/Cas9 System in Vitro
Hairui Zhang et al.
MOLECULAR PHARMACEUTICS (2018)
Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Therapeutics
Brittany E. Givens et al.
AAPS JOURNAL (2018)
BRAF peptide vaccine facilitates therapy of murine BRAF-mutant melanoma
Qi Liu et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2018)
Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA
Jason B. Miller et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Targeted delivery of CRISPR/Cas9 to prostate cancer by modified gRNA using a flexible aptamer-cationic liposome
Shuai Zhen et al.
ONCOTARGET (2017)
Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications
Chang Liu et al.
JOURNAL OF CONTROLLED RELEASE (2017)
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
Hao Yin et al.
NATURE BIOTECHNOLOGY (2017)
Advances in the delivery of RNA therapeutics: from concept to clinical reality
James C. Kaczmarek et al.
GENOME MEDICINE (2017)
Nanoparticles for CRISPR-Cas9 delivery
Zachary Glass et al.
NATURE BIOMEDICAL ENGINEERING (2017)
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair
Kunwoo Lee et al.
NATURE BIOMEDICAL ENGINEERING (2017)
Live Visualization of HIV-1 Proviral DNA Using a Dual-Color-Labeled CRISPR System
Yingxin Ma et al.
ANALYTICAL CHEMISTRY (2017)
Targeted Delivery of CRISPR/Cas9-Mediated Cancer Gene Therapy via Liposome-Templated Hydrogel Nanoparticles
Zeming Chen et al.
ADVANCED FUNCTIONAL MATERIALS (2017)
Cytosolic and Nuclear Delivery of CRISPR/Cas9-ribonucleoprotein for Gene Editing Using Arginine Functionalized Gold Nanoparticles
Rubul Mout et al.
BIO-PROTOCOL (2017)
CRISPR/Cas9-Based Genome Editing for Disease Modeling and Therapy: Challenges and Opportunities for Nonviral Delivery
Hong-Xia Wang et al.
CHEMICAL REVIEWS (2017)
Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of α-tocopheryl succinate-based polyphosphoester copolymers
Feng-qian Chen et al.
ACTA PHARMACOLOGICA SINICA (2017)
In Vivo Delivery of CRISPR/Cas9 for Therapeutic Gene Editing: Progress and Challenges
Rubul Mout et al.
BIOCONJUGATE CHEMISTRY (2017)
Nonviral Genome Editing Based on a Polymer-Derivatized CRISPR Nanocomplex for Targeting Bacterial Pathogens and Antibiotic Resistance
Yoo Kyung Kang et al.
BIOCONJUGATE CHEMISTRY (2017)
Direct Cytosolic Delivery of CRISPR/Cas9-Ribonucleoprotein for Efficient Gene Editing
Rubul Mout et al.
ACS NANO (2017)
A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo
Chao Jiang et al.
CELL RESEARCH (2017)
Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy
Chengzu Long et al.
SCIENCE (2016)
In vivo gene editing in dystrophic mouse muscle and muscle stem cells
Mohammadsharif Tabebordbar et al.
SCIENCE (2016)
Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs
James C. Kaczmarek et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Membrane Microdomain Structures of Liposomes and Their Contribution to the Cellular Uptake Efficiency into HeLa Cells
Yoshinori Onuki et al.
MOLECULAR PHARMACEUTICS (2016)
Engineered Viruses as Genome Editing Devices
Xiaoyu Chen et al.
MOLECULAR THERAPY (2016)
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
Daniel P. Dever et al.
NATURE (2016)
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
Hao Yin et al.
NATURE BIOTECHNOLOGY (2016)
Editing the epigenome: technologies for programmable transcription and epigenetic modulation
Pratiksha I. Thakore et al.
NATURE METHODS (2016)
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles
Ming Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
Konstantinos Tzelepis et al.
CELL REPORTS (2016)
Expressing Transgenes That Exceed the Packaging Capacity of Adeno-Associated Virus Capsids
Kyle Chamberlain et al.
HUMAN GENE THERAPY METHODS (2016)
Glycyrrhetinic acid-decorated and reduction-sensitive micelles to enhance the bioavailability and anti-hepatocellular carcinoma efficacy of tanshinone IIA
Fengqian Chen et al.
BIOMATERIALS SCIENCE (2016)
Intracellular delivery of the PTEN protein using cationic lipidoids for cancer therapy
Sarah A. Altinoglu et al.
BIOMATERIALS SCIENCE (2016)
Preparation, characterization, and anticancer efficacy of evodiamine-loaded PLGA nanoparticles
Lidi Zou et al.
DRUG DELIVERY (2016)
Chemical Biology Approaches to Genome Editing: Understanding, Controlling, and Delivering Programmable Nucleases
Johnny H. Hu et al.
CELL CHEMICAL BIOLOGY (2016)
Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing
Wujin Sun et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication
Chunsheng Dong et al.
ANTIVIRAL RESEARCH (2015)
CRISPR genome engineering and viral gene delivery: A case of mutual attraction
Florian Schmidt et al.
BIOTECHNOLOGY JOURNAL (2015)
Cancer-Associated Protein Kinase C Mutations Reveal Kinase's Role as Tumor Suppressor
Corina E. Antal et al.
CELL (2015)
Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds
Jesse G. Zalatan et al.
CELL (2015)
Harnessing the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated Cas9 system to disrupt the hepatitis B virus
S. Zhen et al.
GENE THERAPY (2015)
Delivery and Specificity of CRISPR/Cas9 Genome Editing Technologies for Human Gene Therapy
Jennifer L. Gori et al.
HUMAN GENE THERAPY (2015)
Challenges in CRISPR/CAS9 Delivery: Potential Roles of Nonviral Vectors
Ling Li et al.
HUMAN GENE THERAPY (2015)
Polymeric Nanocarriers for Non-Viral Gene Delivery
Ling Li et al.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2015)
Rapid and highly efficient mammalian cell engineering via Cas9 protein transfection
Xiquan Liang et al.
JOURNAL OF BIOTECHNOLOGY (2015)
Nucleolin targeting AS1411 aptamer modified pH-sensitive micelles for enhanced delivery and antitumor efficacy of paclitaxel
Jinming Zhang et al.
NANO RESEARCH (2015)
Combinatorial library strategies for synthesis of cationic lipid-like nanoparticles and their potential medical applications
Sarah Altinoglu et al.
NANOMEDICINE (2015)
Tumor pHe-triggered charge-reversal and redox-responsive nanoparticles for docetaxel delivery in hepatocellular carcinoma treatment
Fengqian Chen et al.
NANOSCALE (2015)
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
Van Trung Chu et al.
NATURE BIOTECHNOLOGY (2015)
Therapeutic genome editing: prospects and challenges
David Benjamin Turitz Cox et al.
NATURE MEDICINE (2015)
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
Kathrin Schumann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Cas9-mediated targeting of viral RNA in eukaryotic cells
Aryn A. Price et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling
Marc Zuckermann et al.
NATURE COMMUNICATIONS (2015)
CRISPR genome engineering and viral gene delivery: A case of mutual attraction
Florian Schmidt et al.
BIOTECHNOLOGY JOURNAL (2015)
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
John A. Zuris et al.
NATURE BIOTECHNOLOGY (2015)
CRISPR/Cas9-mediated genome engineering: An adeno-associated viral (AAV) vector toolbox
Elena Senis et al.
BIOTECHNOLOGY JOURNAL (2014)
Development and Applications of CRISPR-Cas9 for Genome Engineering
Patrick D. Hsu et al.
CELL (2014)
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
Hao Yin et al.
NATURE BIOTECHNOLOGY (2014)
Non-viral vectors for gene-based therapy
Hao Yin et al.
NATURE REVIEWS GENETICS (2014)
CRISPR-Cas systems: beyond adaptive immunity
Edze R. Westra et al.
NATURE REVIEWS MICROBIOLOGY (2014)
The new frontier of genome engineering with CRISPR-Cas9
Jennifer A. Doudna et al.
SCIENCE (2014)
Synthesizing AND gate genetic circuits based on CRISPR-Cas9 for identification of bladder cancer cells
Yuchen Liu et al.
NATURE COMMUNICATIONS (2014)
Genetics and genomics of Parkinson's disease
Michelle K. Lin et al.
GENOME MEDICINE (2014)
Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
Steven Lin et al.
ELIFE (2014)
A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification
Syandan Chakraborty et al.
STEM CELL REPORTS (2014)
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
Lei S. Qi et al.
CELL (2013)
One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
Hui Yang et al.
CELL (2013)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert et al.
CELL (2013)
Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients
Gerald Schwank et al.
CELL STEM CELL (2013)
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali et al.
NATURE BIOTECHNOLOGY (2013)
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
NATURE BIOTECHNOLOGY (2013)
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system
David Bikard et al.
NUCLEIC ACIDS RESEARCH (2013)
Minimal Self Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles
Pia L. Rodriguez et al.
SCIENCE (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
Hirotaka Ebina et al.
SCIENTIFIC REPORTS (2013)
Cholesterol-Dependent Macropinocytosis and Endosomal Escape Control the Transfection Efficiency of Lipoplexes in CHO Living Cells
Francesco Cardarelli et al.
MOLECULAR PHARMACEUTICS (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Strategies for extended serum half-life of protein therapeutics
Roland E. Kontermann
CURRENT OPINION IN BIOTECHNOLOGY (2011)
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
H. Cabral et al.
NATURE NANOTECHNOLOGY (2011)
State-of-the-art gene-based therapies: the road ahead
Mark A. Kay
NATURE REVIEWS GENETICS (2011)
Exploring the Genomes of Cancer Cells: Progress and Promise
Michael R. Stratton
SCIENCE (2011)
Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
Katrin Knop et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Polymer- and lipid-based nanoparticle therapeutics for the treatment of liver diseases
Lanjuan Li et al.
NANO TODAY (2010)
Nonviral Vectors for Gene Delivery
Meredith A. Mintzer et al.
CHEMICAL REVIEWS (2009)
Knocking down barriers: advances in siRNA delivery
Kathryn A. Whitehead et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Factors affecting the clearance and biodistribution of polymeric nanoparticles
Frank Alexis et al.
MOLECULAR PHARMACEUTICS (2008)
Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses
Lars Bertram et al.
NATURE REVIEWS NEUROSCIENCE (2008)
Cationic liposomal lipids: From gene carriers to cell signaling
Caroline Lonez et al.
PROGRESS IN LIPID RESEARCH (2008)
Small CRISPR RNAs guide antiviral defense in prokaryotes
Stan J. J. Brouns et al.
SCIENCE (2008)
CRISPR provides acquired resistance against viruses in prokaryotes
Rodolphe Barrangou et al.
SCIENCE (2007)
Targeting of nanoparticles to the clathrin-mediated endocytic pathway
Oshrat Harush-Frenkel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Bile acid-oligopeptide conjugates interact with DNA and facilitate transfection
Phillip E. Kish et al.
MOLECULAR PHARMACEUTICS (2007)
The role of dioleoylphosphaticlylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route
Y Hattori et al.
JOURNAL OF CONTROLLED RELEASE (2005)
Design and development of polymers for gene delivery
DW Pack et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Polyethylenimine-graft-poly(ethylene glycol) copolymers:: Influence of copolymer block structure on DNA complexation and biological activities as gene delivery system
H Petersen et al.
BIOCONJUGATE CHEMISTRY (2002)
A Toll-like receptor recognizes bacterial DNA
H Hemmi et al.
NATURE (2000)
Share Paper
