Journal
TRENDS IN PLANT SCIENCE
Volume 24, Issue 12, Pages 1083-1093Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tplants.2019.09.005
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Funding
- Biotechnology and Biological Sciences Research Council [BB/S003584/1]
- Biotechnology and Biological Sciences Research Council [BB/S003584/1] Funding Source: researchfish
- BBSRC [BB/S001190/1, BB/S003584/1] Funding Source: UKRI
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Size is a fundamental property that must be tightly regulated to ensure that cells and tissues function efficiently. Dynamic size control allows unicellular organisms to adapt to environmental changes, but cell size is also integral to multicellular development, affecting tissue size and structure. Despite clear evidence for homeostatic cell size maintenance, we are only now beginning to understand cell size regulation in the actively dividing meristematic tissues of higher plants. We discuss here how coupled advances in live cell imaging and modelling are uncovering dynamic mechanisms for size control mediated at the cellular level. We argue that integrated models of cell growth and division will be necessary to predict cell size and fully understand multicellular growth and development.
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