Journal
TRENDS IN MOLECULAR MEDICINE
Volume 26, Issue 1, Pages 6-7Publisher
CELL PRESS
DOI: 10.1016/j.molmed.2019.11.004
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Imported across the plasma membrane by SLC1A5, glutamine has emerged as a metabolic fuel that is catabolized by mitochondria) glutaminase to support tumor growth. The missing link between cytoplasmic and mitochondrial glutamine metabolism is now provided by Yoo et al., identifying the rinitochondrial glutamine importer as a variant of SLC1A5.
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