Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 45, Issue 3, Pages 179-+Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2019.12.004
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- National Institutes of Health [K00CA222986]
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Lactate is an end product of glucose metabolism, which serves metabolic and nonmetabolic functions. A new study by Zhang et al. establishes a novel function for lactate whereby it is utilized in a new histone modification, histone lysine lactylation, to regulate gene expression in macrophages.
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