Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 45, Issue 4, Pages 347-364Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2019.11.006
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Funding
- Russian Science Foundation [19-15-00125, 190345, 181301]
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Autophagy is an evolutionarily conserved process whereby damaged and redundant components of the cell are degraded in structures called autophagolysosomes. Currently, three main types of autophagy are recognized: macroautophagy, microautophagy, and chaperone-mediated autophagy (CMA). However, we still know little about some specific types of autophagy that are linked to various intracellular compartments and their roles in the physiology of the whole organism and connections to various diseases. Here, we aim to shed light on the latest insights on and mechanisms of several selective forms of autophagy.
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