Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 123, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2019.115742
Keywords
Fluorescence imaging; Cells; Resonance energy transfer; Active small molecules; Fluorescent probe
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Funding
- National Natural Science Foundation of China [21535004, 91753111, 21874084]
- Natural Science Foundation of Shandong Province [ZR2019JQ07]
- Key Research and Development Program of Shandong Province [2018YFJH0502]
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Fluorescence imaging of intracellular active molecules plays an important role in understanding the occurrence and development of diseases. Resonance energy transfer (RET) has been recognized as a powerful technology in the design of fluorescence probes for biological imaging. Here, we summarize the novel approaches to fabrication of RET-based fluorescent probes systems such as the organic molecular fluorescent probe, nano fluorescent probe, protein probe and their recent applications in cellular fluorescence imaging. (C) 2019 Elsevier B.V. All rights reserved.
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