4.4 Article

Facile Synthesis of Oxime Amino Ethers via Lewis Acid Catalyzed S N 2-Type Ring Opening of Activated Aziridines with Aryl Aldehyde Oximes

Journal

SYNLETT
Volume 31, Issue 7, Pages 708-712

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0039-1691596

Keywords

aziridine; oxime; oxime ether; Lewis acid catalyst; S; (N); 2-type ring opening; stereoselectivity

Funding

  1. Department of Science and Technology (DST), India
  2. Council of Scientific and Industrial Research (CSIR), New Delhi, India
  3. University Grants Commission (UGC), New Delhi, India

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A simple strategy to access a wide range of substituted oxime amino ethers in good to high yields via Lewis acid catalyzed S (N) 2-type ring opening of activated aziridines with aryl aldehyde oximes is reported.

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