Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 304, Issue -, Pages -Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2019.127415
Keywords
Tape; Urine; Urinalysis; Colorimetric sensor array
Funding
- National Natural Science Foundation of China [21804007, 21890742]
- Beijing Natural Science Foundation [2184109]
- Fundamental Research Funds for Central Universities [FRF-TP-17-066A1, FRF-BR-18-009B]
- National Postdoctoral Innovative Talents Support Program of China [BX20180036]
- China Postdoctoral Science Foundation [2019M650479]
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Recent advances in biofluids monitoring have positioned urine as a non-invasive candidate for clinical diagnosis. In this paper, we employ adhesive tapes with indicator-functionalized microarrays for rapid urinalysis. Such tape-based sensor combines advantages of flexibility, adhesive and waterproof functionality in a platform, which is simply prepared by physical punching, fabrics filling and indicators modification. The simulated urine flow can be captured and penetrated in the tape-based microarrays for rapid detection of multiplexed markers such as glucose, nitrite, protein and phenylpyruvate with a smartphone-assisted colorimetric screening method. As a user-friendly point-of-care testing (POCT) approach, such tape-based sensor is ideally favorable for the early disease warning toward the patients of urinary incontinence and infants.
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