4.6 Article

Nanoparticles guided drug delivery and imaging in gastric cancer

Journal

SEMINARS IN CANCER BIOLOGY
Volume 69, Issue -, Pages 69-76

Publisher

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcancer.2020.01.006

Keywords

Gastric cancer; Nanoparticles; Nanotherapeutics; Imaging; Controlled drug delivery

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Gastric cancer is a deadly malignancy worldwide, and nanoparticle (NP) technology offers potential for novel therapeutic methods. NPs play a significant role in multifunctional imaging and drug delivery, providing advantages over conventional anti-cancer medications.
Gastric cancer represents a deadly malignancy worldwide, yet current therapeutic regimens remain ineffective. Nanoparticle (NP)-based solutions could allow the design of novel therapeutic methods to eliminate this fatal disease. NPs typically carry out a significant role in multifunctional, multimodal imaging, and drug delivery carriers. In the recent decade, they have emerged as candidate approaches for the design of novel treatment strategies. Tumor nanotherapeutics characteristically possess various distinct advantages compared to conventional anti-cancer medications, which suffer from nonspecific bio-distribution, low solubility, and poor bioavailability. In this review, we will discuss the application of NPs in diagnosis and controlled drug delivery in gastric cancer (GC). We will focus on various NPs-based strategies employed against GC.

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