4.0 Article

Preparation of Aerogel Materials Based on Alginate-Chitosan Interpolymer Complex Using Supercritical Fluids

Journal

RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B
Volume 13, Issue 7, Pages 1121-1124

Publisher

MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1990793119070224

Keywords

sodium alginate; chitosan; supercritical drying; aerogel; interpolymer complex; levomycetin

Funding

  1. RF Government [AAAA-A18-118012390231-9]

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Aerogel materials based on the interpolymer complex of alginate with chitosan using supercritical fluids technology were obtained. It was established that obtained aerogels have a developed mesoporous structure and a specific surface area of up to 243 m(2)/g. The average pore size equals 14.8 nm. The possibility of using the aerogels with the inclusion of antibiotic levomycetin as a basis for creating wound dressings was shown. It was estimated that slow release of the drug (70% during 5 h) from the aerogel matrix provides prolonged and safe supply of the drug to the surface of a wound.

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