Related references
Note: Only part of the references are listed.Dual DNA topoisomerase 1 and tyrosyl-DNA phosphodiesterase 1 inhibition for improved anticancer activity
Alexandra Zakharenko et al.
MEDICINAL RESEARCH REVIEWS (2019)
Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments
Evgcnii S. Mozhaitsev et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2019)
Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topotecan on in vivo tumor models
A. L. Zakharenko et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors
Konstantin Yu. Ponomarev et al.
BIOORGANIC CHEMISTRY (2018)
Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors
Oksana V. Salomatina et al.
MOLECULES (2018)
Synthesis and evaluation of aryliden- and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors
Olga Zakharova et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold
Nikolai S. Li-Zhulanov et al.
MOLECULES (2018)
Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl-DNA Phosphodiesterase 2 (Tdp2)
Ping Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Achyrodimer F, a tyrosyl-DNA phosphodiesterase I inhibitor from an Australian fungus of the family Cortinariaceae
Li-Wen Tian et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
New inhibitors of tyrosyl-DNA phosphodiesterase I (Tdp 1) combining 7-hydroxycoumarin and monoterpenoid moieties
Tatyana Khomenko et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2016)
Tyrosyl-DNA Phosphodiesterase 1 Inhibitors: Usnic Acid Enamines Enhance the Cytotoxic Effect of Camptothecin
Alexandra Zakharenko et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Discovery of highly potent analgesic activity of isopulegol-derived (2R,4aR,7R,8aR)-4,7-dimethyl-2-(thiophen-2-yl)octahydro-2H-chromen-4-ol
Ekaterina Nazimova et al.
MEDICINAL CHEMISTRY RESEARCH (2016)
Synthesis and biological evaluation of novel tyrosyl-DNA phosphodiesterase 1 inhibitors with a benzopentathiepine moiety
Alexandra Zakharenko et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
A synthesis, in silico, in vitro and in vivo study of thieno[2,3-b]pyridine anticancer analogues
Homayon J. Arabshahi et al.
MEDCHEMCOMM (2015)
Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target
Evan Q. Comeaux et al.
DRUG METABOLISM REVIEWS (2014)
Diamidine Compounds for Selective Inhibition of Protein Arginine Methyltransferase 1
Leilei Yan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) inhibitors
Shar-yin N. Huang et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2011)
AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1
Natalia A. Lebedeva et al.
FEBS LETTERS (2011)
Tdp1 protects against oxidative DNA damage in non-dividing fission yeast
Samia Ben Hassine et al.
EMBO JOURNAL (2009)
OLEX2: a complete structure solution, refinement and analysis program
Oleg V. Dolomanov et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2009)
Empirical Scoring Functions for Advanced Protein-Ligand Docking with PLANTS
Oliver Korb et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2009)
Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay
Christophe Marchand et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Benchmarking the reliability of QikProp. Correlation between experimental and predicted values
Leukothea Ioakimidis et al.
QSAR & COMBINATORIAL SCIENCE (2008)
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1
Smitha Antony et al.
NUCLEIC ACIDS RESEARCH (2007)
Topoisomerase I inhibitors: camptothecins and beyond
Yves Pommier
NATURE REVIEWS CANCER (2006)
General and targeted statistical potentials for protein-ligand interactions
WTM Mooij et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)
Announcing the worldwide Protein Data Bank
H Berman et al.
NATURE STRUCTURAL BIOLOGY (2003)
Improved protein-ligand docking using GOLD
ML Verdonk et al.
PROTEINS-STRUCTURE FUNCTION AND GENETICS (2003)
Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures
DR Davies et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
The Cambridge Structural Database: a quarter of a million crystal structures and rising
FH Allen
ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE (2002)
The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily
H Interthal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)