Journal
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
Volume 30, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.pdpdt.2019.101603
Keywords
Actinic keratosis; Nonmelanoma cancer; 5-aminolevulinic acid; Methyl aminolevulinate acid; Photodynamic Thrapy
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Funding
- FAPESP [CEPOF 13/072761]
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The objective of this study was to evaluate and compare the clinical response to PDT (Photodynamic Therapy) in field cancerization using two aminolevulinate derivatives. Forty patients with multiple actinic keratosis (AK) on forearms and hands scattered received two sessions of ALA and MAL-PDT at 630 nm (36 J/cm(2)). The AK clearance rate was 72 % for both drugs with a significant decrease in AK observed clinically (p < 00,001). Clinical improvement in field cancerization using two aminolevulinate derivatives in PDT is proven with no significant difference in the efficacy of drugs.
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