4.4 Review

Protein energy wasting; what is it and what can we do to prevent it?

Journal

PEDIATRIC NEPHROLOGY
Volume 36, Issue 2, Pages 287-294

Publisher

SPRINGER
DOI: 10.1007/s00467-019-04424-2

Keywords

Protein energywasting; Chronic kidney disease; Cachexia

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Protein energy wasting (PEW) is a condition characterized by poor growth, muscle wasting, and preservation of body fat, resulting from chronic inflammation and inadequate nutritional intake. This review discusses the causes and potential preventative therapies for PEW.
Some children with declining height and BMI SDS fail to respond to optimisation of nutritional intake. As well as poor growth, they have muscle wasting and relative preservation of body fat. This is termed protein energy wasting (PEW). The process results from an interaction of chronic inflammation alongside poor nutritional intake. This review discusses the causes and potential preventative therapies for PEW.

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