Journal
ORGANIC LETTERS
Volume 22, Issue 2, Pages 689-693Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b04472
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Funding
- Council of Scientific and Industrial Research (CSIR), New Delhi
- University of Grants Commission (UGC), New Delhi [IICT/Pubs./2019/424]
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A novel strategy for the synthesis of 3-hydroxycarbazoles involving the consecutive propargylation/palladium-catalyzed hydroxylative benzannulation of indole-2-carbonyls with propargylic alcohols has been exploited. This one-pot procedure leads to a wide range of substituted 3-hydroxycarbazoles in high yield with a broad substrate scope. The method was further extended to access furano-carbazole derivatives from dialkynols via tandem annulations.
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