Journal
MOLECULES
Volume 25, Issue 2, Pages -Publisher
MDPI
DOI: 10.3390/molecules25020287
Keywords
iridoids; phytochemistry; biological activities; pharmacokinetics
Funding
- National Natural Science Foundation of China [81874336, 81760776]
- Natural Science Foundation of Inner Mongolia Autonomous Region [2018ZD13]
- 2018 Chinese medicine public health service subsidy special the fourth survey on Chinese materia medica resource [[2018] 43]
- China Agriculture Research System [CARS-21]
Ask authors/readers for more resources
Iridoids are a class of active compounds that widely exist in the plant kingdom. In recent years, with advances in phytochemical research, many compounds with novel structure and outstanding activity have been identified. Iridoid compounds have been confirmed to mainly exist as the prototype and aglycone and Iota and II metabolites, by biological transformation. These metabolites have been shown to have neuroprotective, hepatoprotective, anti-inflammatory, antitumor, hypoglycemic, and hypolipidemic activities. This review summarizes the new structures and activities of iridoids identified locally and globally, and explains their pharmacokinetics from the aspects of absorption, distribution, metabolism, and excretion according to the differences in their structures, thus providing a theoretical basis for further rational development and utilization of iridoids and their metabolites.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available