Journal
MOLECULAR CELL
Volume 77, Issue 2, Pages 207-209Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2019.12.018
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- NIGMS NIH HHS [R35 GM133462] Funding Source: Medline
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Live-cell RNA imaging is a powerful approach to observe the real-time dynamics of RNA metabolism. Two recent papers describe an optimized fluorescence-based CRISPR-Cas13 approach to image colocalized or repeat-containing RNAs in real time, as well as demonstrate simultaneous RNA-DNA labeling by using Cas13 and Cas9 in tandem.
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