Transient enhanced cell division by blocking DNA synthesis in Escherichia coli

Duplication of the bacterial nucleoid is necessary for cell division hence specific arrest of DNA replication inhibits divisions culminating in filamentation. nucleoid dispersion and appearance of a-nucleated cells. It is demonstrated here that during the first 10min however, Escherichia coli enhanced residual divisions: the proportion of constricted cells doubled (to 40%), nudeolds contracted and cells remodelled dimensions: length decreased and width increased. The preliminary data provides further support to the existence of temporal and spatial couplings between the nucleoid/replisome and the sacculus/divisome, and is consistent with the idea that bacillary bacteria modulate width during the division process exclusively.