Journal
MICROBIAL PATHOGENESIS
Volume 140, Issue -, Pages -Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.micpath.2019.103931
Keywords
Dietary fiber; Probiotics; Infectious diseases; Gut microbes
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Funding
- National Natural Science Foundation of China [81871734]
- Jiangsu Privincial Medical Talent [ZDRCA2016053]
- Six talent peaks project of Jiangsu Province [WSN135]
- Advanced health talent of six-one project of Jiangsu Province [LGY2016042]
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Although antibiotics are commonly used to treat infectious diseases, emergence of antibiotic resistant strains highlights the necessity for developing novel alternative approaches. Meanwhile, clinically, antibiotics can destroy the gut microbes balance, which is not conducive to the recovery of infectious disorders. As a result, recent studies have begun to explore potential prevention and treatment methods for infectious diseases, starting with more readily available dietary fiber and probiotics. Moreover, researches have shown the personalized nature of host responses to dietary fiber intervention, with outcomes being dependent on individual pre-treatment gut microbes. In this review, we will focus on the roles of dietary fiber and probiotics on infectious diseases, how probiotics and dietary fiber work on infectious diseases and then explore their mechanisms, so as to guide clinical consideration of new therapies for infectious diseases.
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