Related references
Note: Only part of the references are listed.PFM-Like Enzymes Are a Novel Family of Subclass B2 Metallo-β-Lactamases from Pseudomonas synxantha Belonging to the Pseudomonas fluorescens Complex
Laurent Poirel et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2020)
Interplay between β-lactamases and new β-lactamase inhibitors
Karen Bush et al.
NATURE REVIEWS MICROBIOLOGY (2019)
X-ray Crystallography Deciphers the Activity of Broad-Spectrum Boronic Acid β-Lactamase Inhibitors
Laura Cendron et al.
ACS MEDICINAL CHEMISTRY LETTERS (2019)
Novel Mercapto Propionamide Derivatives with Potent New Delhi Metallo-β-Lactamase-1 Inhibitory Activity and Low Toxicity
Zhi Meng et al.
ACS INFECTIOUS DISEASES (2019)
Profiling interactions of vaborbactam with metallo-β-lactamases
Gareth W. Langley et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)
Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo-β-Lactamases
Allie Y. Chen et al.
CHEMMEDCHEM (2019)
H2depda: An acyclic adjuvant potentiates meropenem activity in vitro against metallo-β-lactamase-producing enterobacterales
Xiu-Fang Shi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
β-Lactamases and β-Lactamase Inhibitors in the 21st Century
Catherine L. Tooke et al.
JOURNAL OF MOLECULAR BIOLOGY (2019)
Drug delivery systems designed to overcome antimicrobial resistance
Thanh-Nhat Pham et al.
MEDICINAL RESEARCH REVIEWS (2019)
Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery
Nicholas J. Torelli et al.
ACS INFECTIOUS DISEASES (2019)
Will morphing boron-based inhibitors beat the β-lactamases?
Alen Krajnc et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2019)
Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad Spectrum, Dual-Action Inhibitors of Metallo- and Serine-β-lactamases
Yao-Ling Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
A DNA aptamer reveals an allosteric site for inhibition in metallo-β-lactamases
Nazmul H. Khan et al.
PLOS ONE (2019)
4-Amino-2-Sulfanylbenzoic Acid as a Potent Subclass B3 Metallo-β-Lactamase-Specific Inhibitor Applicable for Distinguishing Metallo-β-Lactamase Subclasses
Jun-ichi Wachino et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2019)
Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases
Orville A. Pemberton et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases
Alen Krajnc et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Metal-free directed sp2-C-H borylation
Jiahang Lv et al.
NATURE (2019)
The antimicrobial peptide thanatin disrupts the bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase
Bo Ma et al.
NATURE COMMUNICATIONS (2019)
Azolylthioacetamides as potential inhibitors of New Delhi metallo-β-lactamase-1 (NDM-1)
Xiao-Long Liu et al.
JOURNAL OF ANTIBIOTICS (2019)
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model
Simon Leiris et al.
ACS INFECTIOUS DISEASES (2019)
Bacterial zincophore [S,S]-ethylenediamine-N,N '-disuccinic acid is an effective inhibitor of MBLs
Anna Proschak et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2018)
Antibacterial and beta-Lactamase Inhibitory Activity of Monocyclic beta-Lactams
Lena Decuyper et al.
MEDICINAL RESEARCH REVIEWS (2018)
Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-beta-Lactamases
Dominik Buettner et al.
ACS INFECTIOUS DISEASES (2018)
ACG Clinical Guideline: Treatment of Helicobacter pylori Infection (vol 112, pg 212, 2017)
William D. Chey et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2018)
Discovery of a Novel Metallo-β-Lactamase Inhibitor That Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacteriaceae
Martin Everett et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)
Structural and Kinetic Studies of the Potent Inhibition of Metallo-β-lactamases by 6-Phosphonomethylpyridine-2-carboxylates
Philip Hinchliffe et al.
BIOCHEMISTRY (2018)
Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases
Dong Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Virtual target screening reveals rosmarinic acid and salvianolic acid A inhibiting metallo- and serine-beta-lactamases
Zhu-Jun Yu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
NOTA analogue: A first dithiocarbamate inhibitor of metallo-β-lactamases
En Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
A protein structure-guided covalent scaffold selectively targets the B1 and B2 subclass metallo-β-lactamases
Cheng Chen et al.
CHEMICAL COMMUNICATIONS (2018)
Cell-Wall Recycling of the Gram-Negative Bacteria and the Nexus to Antibiotic Resistance
David A. Dik et al.
CHEMICAL REVIEWS (2018)
Cyclobutanone Mimics of Intermediates in Metallo-beta-Lactamase Catalysis
Martine I. Abboud et al.
CHEMISTRY-A EUROPEAN JOURNAL (2018)
An update on beta-lactamase inhibitor discovery and development
Jean-Denis Docquier et al.
DRUG RESISTANCE UPDATES (2018)
((S)-3-Mercapto-2-methylpropanamido)acetic acid derivatives as metallo-β-lactamase inhibitors: Synthesis, kinetic and crystallographic studies
Sha Liu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors
Ricky Cain et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters
Lin-Cheng Ju et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Rhodanine as a Potent Scaffold for the Development of Broad Spectrum Metallo-β-lactamase inhibitors
Yang Xiang et al.
ACS MEDICINAL CHEMISTRY LETTERS (2018)
Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors
Runming Wang et al.
NATURE COMMUNICATIONS (2018)
Rh(III)-Catalyzed directed C-H carbenoid coupling reveals aromatic bisphosphonates inhibiting metallo- and Serine-beta-lactamases
Chen Zhang et al.
ORGANIC CHEMISTRY FRONTIERS (2018)
Dithiocarbamates: Efficient metallo-β-lactamase inhibitors with good antibacterial activity when combined with meropenem
Ming-Ming Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Virtual Screening and Experimental Testing of B1 Metallo-β-lactamase Inhibitors
Joon S. Kang et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2018)
Differential active site requirements for NDM-1 β-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics
Zhizeng Sun et al.
NATURE COMMUNICATIONS (2018)
Metallo-β-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding
Susann Skagseth et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses
Guo-Bo Li et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2017)
Beta-lactamase database (BLDB) - structure and function
Thierry Naas et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2017)
Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1
Allie Y. Chen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Total Syntheses of Natural Metallophores Staphylopine and Aspergillomarasmine A
Jian Zhang et al.
JOURNAL OF ORGANIC CHEMISTRY (2017)
Predictive compound accumulation rules yield a broad - spectrum antibiotic
Michelle F. Richter et al.
NATURE (2017)
Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis
Alena Stsiapanava et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors
Guo-Bo Li et al.
CHEMICAL SCIENCE (2017)
The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis
Han Feng et al.
NATURE COMMUNICATIONS (2017)
Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase
Xiangzhong Sun et al.
NATURE COMMUNICATIONS (2017)
A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases
Maria-Natalia Lisa et al.
NATURE COMMUNICATIONS (2017)
Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-β-lactamases
Matteo Santucci et al.
SCIENTIFIC REPORTS (2017)
New Delhi Metallo-β-Lactamase 1 Catalyzes Avibactam and Aztreonam Hydrolysis
Christopher T. Lohans et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Lysine-Targeting Covalent Inhibitors
Jonathan Pettinger et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Synthesis and biological evaluation of Aspergillomarasmine A derivatives as novel NDM-1 inhibitor to overcome antibiotics resistance
Jian Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases
Laurent Sevaille et al.
CHEMMEDCHEM (2017)
Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition
Guo-Bo Li et al.
CHEMICAL COMMUNICATIONS (2017)
Cyclic Boronates Inhibit All Classes of β-Lactamases
Samuel T. Cahill et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Total Synthesis and Structural Reassignment of AspergillomarasmineA
Daohong Liao et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Structural Basis of Metallo-beta-Lactamase Inhibition by Captopril Stereoisomers
Juergen Brem et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles
Anne Makena et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Targeted Covalent Inhibitors for Drug Design
Thomas A. Baillie
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Structural Insights into Recognition of Hydrolyzed Carbapenems and Inhibitors by Subclass B3 Metallo-β-Lactamase SMB-1
Jun-ichi Wachino et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Structural and Mutagenic Analysis of Metallo-β-Lactamase IMP-18
Takamitsu Furuyama et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Interaction of Avibactam with Class B Metallo-β-Lactamases
Martine I. Abboud et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Crystal Structures of the Iron-Sulfur Cluster-Dependent Quinolinate Synthase in Complex with Dihydroxyacetone Phosphate, Iminoaspartate Analogues, and Quinolinate
Michael K. Fenwick et al.
BIOCHEMISTRY (2016)
The rapid spread of carbapenem-resistant Enterobacteriaceae
Robert F. Potter et al.
DRUG RESISTANCE UPDATES (2016)
In vitro evaluation of metal chelators as potential metallo- -lactamase inhibitors
R. Azumah et al.
JOURNAL OF APPLIED MICROBIOLOGY (2016)
Structural analysis of human KDM5B guides histone demethylase inhibitor development
Catrine Johansson et al.
NATURE CHEMICAL BIOLOGY (2016)
Interaction of Hydrogen Sulfide with Nitric Oxide in the Cardiovascular System
B. V. Nagpure et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes
Philip Hinchliffe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
The Chemical Biology of Human Metallo-β-Lactamase Fold Proteins
Ilaria Pettinati et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Triazolylthioacetamide: A Valid Scaffold for the Development of New Delhi Metallo-β-Lactmase-1 (NDM-1) Inhibitors
Le Zhai et al.
ACS MEDICINAL CHEMISTRY LETTERS (2016)
Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates
Juergen Brem et al.
NATURE COMMUNICATIONS (2016)
The structure of the metallo-β-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor
Tony Christopeit et al.
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2016)
A review of global initiatives to fight antibiotic resistance and recent antibiotics' discovery
Arpana Sagwal Chaudhary
ACTA PHARMACEUTICA SINICA B (2016)
Variable Active Site Loop Conformations Accommodate the Binding of Macrocyclic Largazole Analogues to HDAC8
Christophe Decroos et al.
BIOCHEMISTRY (2015)
Ebselen as a potent covalent inhibitor of New Delhi metallo-β-lactamase (NDM-1)
Jiachi Chiou et al.
CHEMICAL COMMUNICATIONS (2015)
Overcoming differences: The catalytic mechanism of metallo-β-lactamases
Maria-Rocio Meini et al.
FEBS LETTERS (2015)
NOTA: a potent metallo-β-lactamase inhibitor
Anou M. Somboro et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2015)
Discovery of Novel Inhibitor Scaffolds against the Metallo-β-lactamase VIM-2 by Surface Plasmon Resonance (SPR) Based Fragment Screening
Tony Christopeit et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Approved Drugs Containing Thiols as Inhibitors of Metallo-β-lactamases: Strategy To Combat Multidrug-Resistant Bacteria
Franca-M Klingler et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Discovery of a Cyclic Boronic Acid β-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases
Scott J. Hecker et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by (S)-2-Amino-5-(2-(methylthio)acetimidamido)pentanoic Acid
Wei Tang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
A β-lactamase inhibitor revival provides new hope for old antibiotics
Ken Garber
NATURE REVIEWS DRUG DISCOVERY (2015)
Zinc Chelation by a Small-Molecule Adjuvant Potentiates Meropenem Activity in Vivo against NDM-1-Producing Klebsiella pneumoniae
Shannon B. Falconer et al.
ACS INFECTIOUS DISEASES (2015)
Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM-1 Carbapenemase
Mariano M. Gonzalez et al.
ACS INFECTIOUS DISEASES (2015)
Molecular mechanisms of antibiotic resistance
Jessica M. A. Blair et al.
NATURE REVIEWS MICROBIOLOGY (2015)
X-ray crystallographic analysis of IMP-1 metallo-β-lactamase complexed with a 3-aminophthalic acid derivative, structure-based drug design, and synthesis of 3,6-disubstituted phthalic acid derivative inhibitors
Yukiko Hiraiwa et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Covalent Inhibition of New Delhi Metallo-beta-Lactamase-1 (NDM-1) by Cefaclor
Pei W. Thomas et al.
CHEMBIOCHEM (2014)
Diaryl-Substituted Azolylthioacetamides: Inhibitor Discovery of New Delhi Metallo-β-Lactamase-1 (NDM-1)
Yi-Lin Zhang et al.
CHEMMEDCHEM (2014)
Penicillin-binding proteins: evergreen drug targets
Jean-Marie Frere et al.
CURRENT OPINION IN PHARMACOLOGY (2014)
Crystal Structures of the Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition
Chong Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins
Han Feng et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Chemical con artists foil drug discovery
Jonathan Baell et al.
NATURE (2014)
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance
Andrew M. King et al.
NATURE (2014)
Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition
Juergen Brem et al.
NATURE CHEMISTRY (2014)
Proliferation and significance of clinically relevant β-lactamases
Karen Bush
ANTIMICROBIAL THERAPEUTICS REVIEWS: THE BACTERIAL CELL WALL AS AN ANTIMICROBIAL TARGET (2013)
Structural Insights into the Subclass B3 Metallo-beta-Lactamase SMB-1 and the Mode of Inhibition by the Common Metallo-beta-Lactamase Inhibitor Mercaptoacetate
Jun-ichi Wachino et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Allosteric inhibition of VIM metallo-β-lactamases by a carnelid nanobody
Jean S. Sohier et al.
BIOCHEMICAL JOURNAL (2013)
Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R-thiomandelic acid
Andreas Ioannis Karsisiotis et al.
BIOCHEMICAL JOURNAL (2013)
Structural and Mechanistic Characterization of L-Histidinol Phosphate Phosphatase from the Polymerase and Histidinol Phosphatase Family of Proteins
Swapnil V. Ghodge et al.
BIOCHEMISTRY (2013)
An altered zinc-binding site confers resistance to a covalent inactivator of New Delhi metallo-beta-lactamase-1 (NDM-1) discovered by high-throughput screening
Pei W. Thomas et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Targeting metallo-β-lactamase enzymes in antibiotic resistance
Dustin T. King et al.
FUTURE MEDICINAL CHEMISTRY (2013)
Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)
WeiShen Aik et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Assay Platform for Clinically Relevant Metallo-β-lactamases
Sander S. van Berkel et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
2-Substituted 4,5-dihydrothiazole-4-carboxylic acids are novel inhibitors of metallo-β-lactamases
Pinhong Chen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
New Delhi Metallo-β-Lactamase: Structural Insights into β-Lactam Recognition and Inhibition
Dustin T. King et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Structure of Prokaryotic Polyamine Deacetylase Reveals Evolutionary Functional Relationships with Eukaryotic Histone Deacetylases
Patrick M. Lombardi et al.
BIOCHEMISTRY (2011)
Crystal Structure of Serratia fonticola Sfh-I: Activation of the Nucleophile in Mono-Zinc Metallo-β-Lactamases
Fatima Fonseca et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
HELICOBACTER PYLORI ERADICATION A new, single-capsule bismuth-containing quadruple therapy
Javier P. Gisbert
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2011)
Crystal structure of New Delhi metallo-β-lactamase reveals molecular basis for antibiotic resistance
Dustin King et al.
PROTEIN SCIENCE (2011)
Updated Functional Classification of beta-Lactamases
Karen Bush et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
High-Resolution Crystal Structure of the Subclass B3 Metallo-β-Lactamase BJP-1: Rational Basis for Substrate Specificity and Interaction with Sulfonamides
Jean-Denis Docquier et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor
Ana Conejo-Garcia et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Hydrolysis of Organophosphate Esters: Phosphotriesterase Activity of Metallo-beta-lactamase and Its Functional Mimics
A. Tamilselvi et al.
CHEMISTRY-A EUROPEAN JOURNAL (2010)
Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-β-lactamases
Patricia Lassaux et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Cyclobutanone Analogues of β-Lactams Revisited: Insights into Conformational Requirements for Inhibition of Serine- and Metallo-β-Lactamases
Jarrod W. Johnson et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
The Bacterial Cell Envelope
Thomas J. Silhavy et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
The Structure of the Dizinc Subclass B2 Metallo-β-Lactamase CphA Reveals that the Second Inhibitory Zinc Ion Binds in the Histidine Site
Carine Bebrone et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Structural insights into the design of inhibitors for the L1 metallo-β-lactamase from Stenotrophomonas maltophilia
L. Nauton et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
Benoit M. R. Lienard et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2008)
Crystallographic investigation of the inhibition mode of a VIM-2 metallo-β-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor
Yoshihiro Yamaguchi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
The metallo-ß-lactamase GOB is a mono-Zn(II) enzyme with a novel active site
Jorgelina Moran-Barrio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Competitive inhibitors of the CphA metallo-β-lactamase from Aeromonas hydrophila
L. E. Horsfall et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Antibiotic recognition by binuclear metallo-β-lactamases revealed by X-ray crystallography
J Spencer et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase B
M Adler et al.
BIOCHEMISTRY (2005)
A metallo-β-lactamase enzyme in action:: Crystal structures of the monozinc carbapenemase CphA and its complex with biapenem
G Garau et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Second-generation inhibitors for the metalloprotease neprilysin based on bicyclic heteroaromatic scaffolds: Synthesis, biological activity, and X-ray crystal-structure analysis
S Sahli et al.
HELVETICA CHIMICA ACTA (2005)
Irreversible inhibition of metallo-beta-lactamase (IMP-1) by 3-(3-mercaptopropionylsulfanyl)propionic acid pentafluorophenyl ester
H Kurosaki et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
The 1.5-Å structure of Chryseobacterium meningosepticum zinc β-lactamase in complex with the inhibitor, D-captopril
I García-Sáez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-β-lactamases
DJ Payne et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction
JM Ogle et al.
CHEMISTRY & BIOLOGY (2001)
Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-β-lactamase
JH Toney et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Crystal structure of the IMP-1 metallo β-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor:: Binding determinants of a potent, broad-spectrum inhibitor
NO Concha et al.
BIOCHEMISTRY (2000)
Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 β-lactamase
S Ness et al.
BIOCHEMISTRY (2000)