4.6 Article

Magnetic Fe3O4@PVP nanotubes with high heating efficiency for MRI-guided magnetic hyperthermia applications

Journal

MATERIALS LETTERS
Volume 262, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.matlet.2019.127187

Keywords

Magnetic nanotube; Magnetic resonance imaging; Magnetic hyperthermia

Funding

  1. National Natural Science Foundation of China [51971162, U1933112, 51671146]
  2. Program of Shanghai Technology Research Leader [18XD1423800]
  3. Fundamental Research Funds for the Central Universities [22120180096]

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The Fe3O4@PVP nanotubes have been successfully synthesized in large quantities using a hydrothermal synthesis. The fabricated sample shows a relatively high transverse relaxivity of 97.97 mM(-1)s(-1) for magnetic resonance imaging (MRI) and a high heating efficiency of 5050 W/g for magnetic hyperthermia. The results suggest that the fabricated samples hold a great potential for the MRI-guided magnetic hyperthermia applications in the cancer theranostic fields. In addition, this study also opens the window to explore high efficiency magnetic hyperthermia agents by controlling the shape of the magnetic nanostructures. (C) 2019 Elsevier B.V. All rights reserved.

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