Journal
MACROMOLECULAR RAPID COMMUNICATIONS
Volume 41, Issue 8, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/marc.201900430
Keywords
biomedical applications; graft polymerization; polymeric biomaterials; surface modification
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This review focuses on the attachment of polymer brushes to polymeric biomaterial substrates by chemical surface modification methods for biomedical applications. In the first part of this paper, a general introduction to the synthesis of polymer brushes is given. Thereafter, a comprehensive overview of recent work on the chemical surface modification of polymeric biomaterials, with a focus on grafting-to, grafting-from, and grafting-through strategies, is provided. Finally, some representative cutting-edge biomedical applications of modified polymeric biomaterials, mainly including antifouling materials and biocompatible materials, are highlighted. On the basis of this literature study, a perspective on future trends in this field is provided.
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