Antibacterial and anticavity activity of probiotic Lactobacillus plantarum 200661 isolated from fermented foods against Streptococcus mutans

This study investigated the characteristics of Lactobacillus strains as an oral probiotic. Lactobacillus delbrueckii 200170 and L. plantarum 200661 were isolated from raw crab marinated in soy sauce and fermented tomato kimchi, respectively. L. rharnnosus GG was used as control. L. rhanmosus GG and L. plantarum 200661 survived in gastrointestinal conditions. They could stably produce enzymes and transfer antibiotic resistance. The antibacterial activity of L. rhantnosus GG, L. delbrueckii 200170, and L. plantarum 200661 inhibited three Streptococcus mutans strains. L. plantarum 200661 showed the highest antibacterial activity and inhibited S. morons biofilm formation by 71.8-94.79%. L. plantarum 200661 inhibited glucan formation by 58.4%. L. planmum 200661 could also inhibit the expression levels of biofilm formation and glucan related genes in S. mutans strains. Therefore, L. plantarum 200661 can be used as a biofilm inhibitor and as an oral probiotic in functional foods.