Related references
Note: Only part of the references are listed.Monoclonal Antibodies Targeting Ion Channels and Their Therapeutic Potential
Aurelien Haustrate et al.
FRONTIERS IN PHARMACOLOGY (2019)
Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH4 Pathway
Benjamin J. R. Moore et al.
ACS OMEGA (2019)
Ion channels as therapeutic antibody targets
Catherine J. Hutchings et al.
MABS (2019)
Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets
Kathryn H. Ching et al.
MABS (2018)
Tranilast directly targets NLRP3 to treat inflammasome-driven diseases
Yi Huang et al.
EMBO MOLECULAR MEDICINE (2018)
A Pilot Study of Tranilast for Cardiomyopathy of Muscular Dystrophy
Tsuyoshi Matsumura et al.
INTERNAL MEDICINE (2018)
Novel inhibitor candidates of TRPV2 prevent damage of dystrophic myocytes and ameliorate against dilated cardiomyopathy in a hamster model
Yuko Iwata et al.
Oncotarget (2018)
Transient receptor potential vanilloid 2 function regulates cardiac hypertrophy via stretch-induced activation
Sheryl E. Koch et al.
JOURNAL OF HYPERTENSION (2017)
TRPV2 knockout mice demonstrate an improved cardiac performance following myocardial infarction due to attenuated activity of peri-infarct macrophages
Michal Entin-Meer et al.
PLOS ONE (2017)
The role of transient receptor potential vanilloid 2 channel in cardiac aging
Shannon Jones et al.
AGING CLINICAL AND EXPERIMENTAL RESEARCH (2017)
Dilated Cardiomyopathy Genetic Determinants and Mechanisms
Elizabeth M. McNally et al.
CIRCULATION RESEARCH (2017)
Uricosuric targets of tranilast
Asim K. Mandal et al.
PHARMACOLOGY RESEARCH & PERSPECTIVES (2017)
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC
Piotr Ponikowski et al.
EUROPEAN JOURNAL OF HEART FAILURE (2016)
Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies
Anatoly Shcherbatko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Cryo-electron microscopy structure of the TRPV2 ion channel
Lejla Zubcevic et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Structure of the full-length TRPV2 channel by cryo-EM
Kevin W. Huynh et al.
NATURE COMMUNICATIONS (2016)
Cryo-electron microscopy structure of the TRPV2 ion channel
Lejla Zubcevic et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Endocytosis of ABCG2 drug transporter caused by binding of 5D3 antibody: trafficking mechanisms and intracellular fate
Maciej Studzian et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)
Dystrophic cardiomyopathy: role of TRPV2 channels in stretch-induced cell damage
Charlotte Lorin et al.
CARDIOVASCULAR RESEARCH (2015)
Discovery of Functional Antibodies Targeting Ion Channels
Trevor C. I. Wilkinson et al.
JOURNAL OF BIOMOLECULAR SCREENING (2015)
The Transient Receptor Potential Vanilloid 2 Cation Channel Is Abundant in Macrophages Accumulating at the Peri-Infarct Zone and May Enhance Their Migration Capacity towards Injured Cardiomyocytes following Myocardial Infarction
Michal Entin-Meer et al.
PLOS ONE (2014)
Blockade of sarcolemmal TRPV2 accumulation inhibits progression of dilated cardiomyopathy
Yuko Iwata et al.
CARDIOVASCULAR RESEARCH (2013)
Global metabolomic analysis of heart tissue in a hamster model for dilated cardiomyopathy
Keiko Maekawa et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
2013 ACCF/AHA Guideline for the Management of Heart Failure A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Clyde W. Yancy et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)
Antibody-Mediated Targeting of the Orai1 Calcium Channel Inhibits T Cell Function
Jennifer H. Cox et al.
PLOS ONE (2013)
Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice
Faiez Zannad et al.
EUROPEAN HEART JOURNAL (2012)
Adult onset cardiac dilatation in a transgenic mouse line with Galβ1,3GalNAc α2,3-sialyltransferase II (ST3Gal-II) transgenes: a new model for dilated cardiomyopathy
Osamu Suzuki et al.
PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2011)
Dilated cardiomyopathy
John Lynn Jefferies et al.
LANCET (2010)
Therapeutic antibodies directed at G protein-coupled receptors
Catherine J. Hutchings et al.
MABS (2010)
Therapeutic antibodies for autoimmunity and inflammation
Andrew C. Chan et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Magnetic Separation of Human Podocalyxin-like Protein 1 (hPCLP1)-Positive Cells from Peripheral Blood and Umbilical Cord Blood Using Anti-hPCLP1 Monoclonal Antibody and Protein A Expressed on Bacterial Magnetic Particles
Motoki Kuhara et al.
CELL STRUCTURE AND FUNCTION (2009)
Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models
Yuko Iwata et al.
HUMAN MOLECULAR GENETICS (2009)
Activation of Na+/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure
Tomoe Y. Nakamura et al.
CIRCULATION RESEARCH (2008)
Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxydiphenyl borate
Veronique Juvin et al.
MOLECULAR PHARMACOLOGY (2007)
A polyclonal antibody to the prepore loop of transient receptor potential vanilloid type 1 blocks channel activation
Lana Klionsky et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Protective effects of Ca2+ handling drugs against abnormal Ca2+ homeostasis and cell damage in myopathic skeletal muscle cells
Y Iwata et al.
BIOCHEMICAL PHARMACOLOGY (2005)
New insights into the pathology of inherited cardiomyopathy
SE Hughes et al.
HEART (2005)
A novel mechanism of myocyte degeneration involving the Ca2+-permeable growth factor-regulated channel
Y Iwata et al.
JOURNAL OF CELL BIOLOGY (2003)
Molecular mechanisms of inherited cardiomyopathies
D Fatkin et al.
PHYSIOLOGICAL REVIEWS (2002)
Stretch-activated cation channels in skeletal muscle myotubes from sarcoglycan-deficient hamsters
TY Nakamura et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2001)
Stretch-induced cell damage in sarcoglycan-deficient myotubes
M Sampaolesi et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2001)
The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms
JG Seidman et al.
CELL (2001)