Preparation and slow release kinetics of apple fragrance/β-cyclodextrin inclusion complex

In this study, the optimum preparation conditions for apple fragrance (AF)/beta-cyclodextrin (beta-CD) inclusion complex were determined by single-factor experiments with encapsulation efficiency (EE%) and loading capacity (LC%) as indicators. The results of particle size analysis indicated that the average diameter of the inclusion complex was 3.6 mu m. DSC analysis indicated that the AF/beta-CD inclusion complex had a good stability. The release study showed that the retention rate of the AF was 34.4% 60 days later at 50 degrees C. Avrami's equation was used to analyze the release kinetics of fragrance/beta-CD inclusion complex under different temperatures. The results showed that the release of encapsulated fragrance was between diffusion limiting kinetics and first-order release kinetics at 4 degrees C, and first-order mode release mechanism at 25 and 50 degrees C. These results demonstrated that the stability of encapsulated fragrance was enhanced and achieved the purpose of controlled release.

Automated summary

The study identified the optimal preparation conditions for the apple fragrance/beta-cyclodextrin inclusion complex through single-factor experiments, with an average diameter of 3.6 μm and good stability. The release mechanism was determined to be first-order release kinetics.