Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 141, Issue 51, Pages 20058-20061Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jacs.9b12315
Keywords
-
Categories
Funding
- Pfizer Inc.
- Bristol-Myers Squibb
Ask authors/readers for more resources
A new and practical method has been developed for the transformation of racemic alpha-bromo ketones to chiral alpha-azido and alpha-amino ketones with high enantioselectivity using phase transfer, ion-pair mediated reactions with a recoverable chiral quaternary salt (10 mol %) as catalyst in fluorobenzene-water. The process has been generalized to a variety of other attachments including of C, O, S, and NHR.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available