Journal
JOURNAL OF SEPARATION SCIENCE
Volume 43, Issue 1, Pages 226-240Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.201900769
Keywords
breath analysis; needle trap technology; sample preparation; solid phase microextraction; volatile organic compounds
Categories
Funding
- National Science and Engineering Research Council
Ask authors/readers for more resources
Detection of biomarkers in exhaled breath has been gaining increasing attention as a tool for diagnosis of specific diseases. However, rapid and accurate quantification of biomarkers associated with specific diseases requires the use of analytical methods capable of fast sampling and preconcentration from breath matrix. In this regard, solid phase microextraction and needle trap technology are becoming increasingly popular in the field of breath analysis due to the unique benefits imparted by such methods, such as the integration of sampling, extraction, and preconcentration in a single step. This review discusses recent advances in breath analysis using these sample preparation techniques, providing a summary of recent developments of analytical methods based on breath volatile organic compounds analysis, including the successful identification of various biomarkers related to human diseases.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available