Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 160, Issue 4, Pages 525-529Publisher
SPRINGER
DOI: 10.1007/s10517-016-3212-x
Keywords
mesenchymal stromal cells; dental pulp; SHED cells; tissue engineering
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Funding
- Russian Science Foundation [14-25-00055]
- Program for Basic Research State Academies of Sciences
- Russian Science Foundation [14-25-00055] Funding Source: Russian Science Foundation
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We performed a comparative study of cell phenotype and proliferation and migration activities in vitro of mesenchymal stromal cells from human exfoliated deciduous teeth (SHED cells) from three donors. In the primary cultures, the cells of different donors had the same morphology and cytophenotype, but differed by proliferative and migration capacities. The results indicate that individual mesenchymal stromal cells cultures can differ considerably by important cell properties, and this should be considered when evaluating their potential therapeutic efficacy and in experimental studies.
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