Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 177, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.jpba.2019.112879
Keywords
Artichoke leaf extracts; European Pharmacopoeia; Hot water extraction; Sonication
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Globe artichoke (Cynara cardunculus var. scolymus L.) is not only used as a vegetable and ornamental plant, but also as important medicinal plant for the treatment of dyspeptic disorders. The European Pharmacopoeia describes a method for the quality assessment of dry artichoke leaves, which is time-consuming and requires huge amounts of organic solvents. In this study, an ultrasound-assisted extraction method was studied, which proved to be more efficient than the standard protocol of the European Pharmacopoeia, since it led to comparable results, was faster and easier to handle, and was more sustainable due to a reduced need for organic solvents. (C) 2019 Elsevier B.V. All rights reserved.
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