Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 85, Issue 5, Pages 3508-3516Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b03234
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Funding
- National Natural Science Foundation of China [21971174, 21772137, 21542015, 21672157]
- PAPD
- Project of Scientific and Technologic Infrastructute of Suzhou [SZS201708]
- Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions [16KJA150002]
- Soochow University
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New practical synthesis of 2-amino-1,3-selenazole with transition metal-free multicomponent reaction is reported here. A series of 2-amino-1,3-selenazole derivatives were afforded by the nucleophilic addition of amines to isoselenocyanate formed in situ, followed by Michael addition reaction and aromatization. The products were isolated from moderate to excellent yields.
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