Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 85, Issue 5, Pages 3349-3357Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b03154
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Funding
- National Natural Science Foundation of China [21602057, 21572051, 21901071, 21971061]
- Opening Fund of Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China)
- Hunan Normal University [KLCBTCMR201707, KLCBTCMR201708]
- Science and Technology Planning Project of Hunan Province [2018TP1017]
- Hong Kong Scholars program [XJ2017009]
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An efficient molecular iodine-catalyzed three component cascade reaction for the construction of 2-phenylnaphtho[2,1-d] selenazoles from naphthalen-2-amine, aldehydes, and selenium powder has been developed. The present approach has the advantages of metal-free conditions, simple operation, and available raw materials. Moreover, the mechanism of the study proved that the reaction underwent a radical process.
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