Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 85, Issue 4, Pages 1915-1926Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.9b02606
Keywords
-
Categories
Funding
- Taishan Scholars Construction Projects of Shandong [tsqn201909131]
- NSFC [21878167]
- Natural Science Foundation of Shandong Province [JQ201604]
- Key Research and Development Program of Shandong Province [2017GSF218073]
- Qingdao Special Research Foundation of Science and Technology [19-6-1-38-nsh]
Ask authors/readers for more resources
Hexafluoroisopropanol has been demonstrated as the versatile promoter for redox-neutral alpha-C(sp(3))-H functionalization of cyclic amines via the cascade [1,5]-hydride transfer/cyclization strategy. A wide range of cyclic amines are functionalized into bioactive tetrahydroquinolines, quinazolines, benzoxazines, and benzotriazepines in moderate to excellent yields. This protocol features additive-free conditions, operational simplicity, and wide substrate scope.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
