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The Protective Effects of Myricetin against Cardiovascular Disease

Journal

JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
Volume 65, Issue 6, Pages 470-476

Publisher

CENTER ACADEMIC PUBL JAPAN
DOI: 10.3177/jnsv.65.470

Keywords

cardioprotective; hypertensive; atherosclerotic; hypoglycemic; hypolipidemic

Funding

  1. National Natural Science Foundation of China [81803570]
  2. Postdoctoral Science Foundation of China [2019M652411]
  3. Shandong Provincial Natural Science Foundation of China [ZR2017BH093]

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Cardiovascular disease (CVD) is the leading cause of death globally, except Africa, and poses a severe health burden worldwide. Both in vitro and in vivo studies have demonstrated the protective effects of myricetin for preventing CVD. For this review, we have assessed the literature from 2009 to 2019 at home and abroad to uncover the protective roles of myricetin for preventing CVD. Myricetin exhibits cardioprotective, anti-hypertensive, anti-atherosclerotic, anti-hyperglycemic, and anti-hyperlipidemic effects. In addition, myricetin may alleviate some of the complications caused by adult-onset diabetes. The combined functions of myricetin allow for the prevention of CVD. This review describes the possible therapeutic benefits of myricetin, along with its potential mechanisms of action, to support the clinical use of the myricetin for the prevention of CVD.

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