Journal
JOURNAL OF NEUROSCIENCE METHODS
Volume 332, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.jneumeth.2019.108539
Keywords
Peripheral nerve interfaces; Peripheral nervous system; Prosthetics; Haptics; motor control; Sensory systems; Proprioception; Plasticity; Learning; Training; Prescriptions; Pain; Bioelectronic medicine; Inflammation
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Background. Peripheral nerve interfaces have emerged as alternative solutions for a variety of therapeutic and performance improvement applications. The Defense Advanced Research Projects Agency (DARPA) has widely invested in these interfaces to provide motor control and sensory feedback to prosthetic limbs, identify non-pharmacological interventions to treat disease, and facilitate neuromodulation to accelerate learning or improve performance on cognitive, sensory, or motor tasks. In this commentary, we highlight some of the design considerations for optimizing peripheral nerve interfaces depending on the application space. We also discuss the ethical considerations that accompany these advances.
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