Journal
JOURNAL OF DERMATOLOGY
Volume 47, Issue 3, Pages 223-235Publisher
WILEY
DOI: 10.1111/1346-8138.15207
Keywords
Behcet's disease; guideline; mucocutaneous lesion; oral aphtous ulcer; treatment
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In the current study, we present guidelines for the diagnosis and treatment of the mucocutaneous lesions of Behcet's disease, which is a chronic inflammatory disease characterized by the involvement of various organs, including mucocutaneous, ocular, vascular, intestinal and central nervous system lesions. It is often identified in the Middle East Mediterranean to East Asia region. Skin manifestations include erythema nodosum, papulopustular lesions and thrombophlebitis, and mucosal manifestations include oral and genital ulcers. These mucocutaneous lesions are characteristically the first signs of Behcet's disease and are important to be recognized for the early diagnosis of the disease. Moreover, these manifestations also recur and persist over the long-term course of the disease. The management of mucocutaneous lesions is important to prevent recurrence. We developed consensus guidelines that provide recommendations for general practitioners and dermatologists and physicians on the management of the mucocutaneous lesions of Behcet's disease.
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