Related references
Note: Only part of the references are listed.Microglia antioxidant systems and redox signalling
F. Vilhardt et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Neuroprotective effects of levetiracetam target xCT in astrocytes in parkinsonian mice
Ikuko Miyazaki et al.
JOURNAL OF NEUROCHEMISTRY (2016)
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
Christopher Southan et al.
NUCLEIC ACIDS RESEARCH (2016)
Effects of the inducible nitric oxide synthase inhibitor aminoguanidine in two different rat models of schizophrenia
Anastasios Lafioniatis et al.
BEHAVIOURAL BRAIN RESEARCH (2016)
Update on monitoring and adverse effects of approved second-generation disease-modifying therapies in relapsing forms of multiple sclerosis
Divyanshu Dubey et al.
CURRENT OPINION IN NEUROLOGY (2016)
Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation
Jacek Zielonka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Curcumin and Health
Mario Pulido-Moran et al.
MOLECULES (2016)
Nitroxide antioxidant as a potential strategy to attenuate the oxidative/nitrosative stress induced by hydrogen peroxide plus nitric oxide in cultured neurons
Ching-Tien Lee et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2016)
Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer's disease
Nurgul Aytan et al.
SCIENTIFIC REPORTS (2016)
Mitochondrial Dysfunction in Alzheimer's Disease and the Rationale for Bioenergetics Based Therapies
Isaac G. Onyango et al.
AGING AND DISEASE (2016)
Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement
Sebastian Altenhofer et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor
Kazufumi Hirano et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease
Aurelija Jucaite et al.
BRAIN (2015)
The role of dietary coconut for the prevention and treatment of Alzheimer's disease: potential mechanisms of action
W. M. A. D. B. Fernando et al.
BRITISH JOURNAL OF NUTRITION (2015)
THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Ligand-gated ion channels
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Transporters
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Overview
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Enzymes
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Carnosic acid protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson's disease: Involvement of antioxidative enzymes induction
Chi-Rei Wu et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2015)
Risk of progressive multifocal leukoencephalopathy in patients with multiple sclerosis
Michele Faulkner
EXPERT OPINION ON DRUG SAFETY (2015)
Therapeutic potential of peroxynitrite decomposition catalysts: a patent review
Lauren M. Slosky et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2015)
Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease
Dominik Haddad et al.
FEBS LETTERS (2015)
A subset of N-substituted phenothiazines inhibits NADPH oxidases
Tamara Seredenina et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Alternative functions of the brain transsulfuration pathway represent an underappreciated aspect of brain redox biochemistry with significant potential for therapeutic engagement
Kenneth Hensley et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Neuroprotective effects of N-acetylcysteine amide on experimental focal penetrating brain injury in rats
Mattias Gunther et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2015)
Improved neuroprotective effects of resveratrol-loaded polysorbate 80-coated poly(lactide) nanoparticles in MPTP-induced Parkinsonism
Gabriela da Rocha Lindner et al.
NANOMEDICINE (2015)
Oxidative and nitrative stress in neurodegeneration
Catherine A. Cobb et al.
NEUROBIOLOGY OF DISEASE (2015)
Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice - Impact on bioavailability
Stephanie Hagl et al.
NEUROCHEMISTRY INTERNATIONAL (2015)
Changes in the mitochondrial antioxidant systems in neurodegenerative diseases and acute brain disorders
Joanna Ruszkiewicz et al.
NEUROCHEMISTRY INTERNATIONAL (2015)
Polymerized nano-curcumin attenuates neurological symptoms in EAE model of multiple sclerosis through down regulation of inflammatory and oxidative processes and enhancing neuroprotection and myelin repair
Maryam Mohajeri et al.
NEUROPHARMACOLOGY (2015)
MPTP-induced parkinsonism in mice alters striatal and nigral xCT expression but is unaffected by the genetic loss of xCT
Eduard Bentea et al.
NEUROSCIENCE LETTERS (2015)
Angiotensin AT2 receptor stimulation inhibits activation of NADPH oxidase and ameliorates oxidative stress in rotenone model of Parkinson's disease in CATH.a cells
Jie Lu et al.
NEUROTOXICOLOGY AND TERATOLOGY (2015)
Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase
Yang Li et al.
ACS MEDICINAL CHEMISTRY LETTERS (2015)
Dimethyl fumarate in the treatment of relapsing-remitting multiple sclerosis: an overview
Roberto Bomprezzi
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2015)
Thiol redox homeostasis in neurodegenerative disease
Gethin J. McBean et al.
REDOX BIOLOGY (2015)
Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: A comparative crossover study.
Bernard Schmitt et al.
REDOX BIOLOGY (2015)
Loss of angiotensin II receptor expression in dopamine neurons in Parkinson's disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation
W. Michael Zawada et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Sulforaphane Ameliorates Neurobehavioral Deficits and Protects the Brain From Amyloid β Deposits and Peroxidation in Mice With Alzheimer-Like Lesions
Rui Zhang et al.
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2015)
System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice
Pinar Mesci et al.
BRAIN (2015)
Strategy to reduce free radical species in Alzheimer's disease: an update of selected antioxidants
Fabio Di Domenico et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2015)
Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease
William M. Johnson et al.
HUMAN MOLECULAR GENETICS (2015)
RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity
Brandon L. Probst et al.
PLOS ONE (2015)
Dimethyl fumarate for multiple sclerosis
Zhu Xu et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2015)
Reduction of CD8+ T lymphocytes in multiple sclerosis patients treated with dimethyl fumarate
Collin M. Spencer et al.
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2015)
Ascorbic acid for the treatment of Charcot-Marie-Tooth disease
Burkhard Gess et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2015)
Mechanisms Contributing to Adverse Cardiovascular Events in Patients with Type 2 Diabetes Mellitus and Stage 4 Chronic Kidney Disease Treated with Bardoxolone Methyl
Melanie P. Chin et al.
AMERICAN JOURNAL OF NEPHROLOGY (2014)
Fingolimod May Support Neuroprotection via Blockade of Astrocyte Nitric Oxide
Emanuela Colombo et al.
ANNALS OF NEUROLOGY (2014)
New Insights on NOX Enzymes in the Central Nervous System
Zeynab Nayernia et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Redox Control of Microglial Function: Molecular Mechanisms and Functional Significance
Ana I. Rojo et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell death
J. M. Dowding et al.
CELL DEATH AND DIFFERENTIATION (2014)
The Effects of Different Antioxidants on the Activity of Cerebrocortical MnSOD and Na,K-ATPase from post mortem Alzheimer's Disease and Age-matched Normal Brains
C. Kairane et al.
CURRENT ALZHEIMER RESEARCH (2014)
NADPH oxidase (NOX2) activity is a modifier of survival in ALS
Giuseppe Marrali et al.
JOURNAL OF NEUROLOGY (2014)
Successful treatment of discoid lupus erythematosus with fumaric acid esters
Athanasios Tsianakas et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2014)
The Study of Mental and Resistance Training (SMART) Study-Resistance Training and/or Cognitive Training in Mild Cognitive Impairment: A Randomized, Double-Blind, Double-Sham Controlled Trial
Maria A. Fiatarone Singh et al.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2014)
Glutathione in multiple sclerosis: More than just an antioxidant?
Andreia N. Carvalho et al.
MULTIPLE SCLEROSIS JOURNAL (2014)
Aminoguanidine treatment ameliorates inflammatory responses and memory impairment induced by amyloid-beta 25-35 injection in rats
Alfonso Diaz et al.
NEUROPEPTIDES (2014)
Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway
Haiyan Lou et al.
NEUROPHARMACOLOGY (2014)
CURCUMIN ABOLISHES MUTANT TDP-43 INDUCED EXCITABILITY IN A MOTONEURON-LIKE CELLULAR MODEL OF ALS
H. Dong et al.
NEUROSCIENCE (2014)
A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2R1441G) transgenic mouse model of Parkinson's disease
Brian P. Dranka et al.
NEUROSCIENCE LETTERS (2014)
S-Allylmercapto-N-acetylcysteine (ASSNAC) protects cultured nerve cells from oxidative stress and attenuates experimental autoimmune encephalomyelitis
Naphtali Savion et al.
NEUROSCIENCE LETTERS (2014)
Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells
Hidemi Yoshida et al.
NEUROSCIENCE RESEARCH (2014)
Thioredoxin System Regulation in the Central Nervous System: Experimental Models and Clinical Evidence
Daniela Silva-Adaya et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
John D. Hayes et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Endothelial NADPH oxidases: which NOX to target in vascular disease?
Grant R. Drummond et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52
Chulman Jo et al.
NATURE COMMUNICATIONS (2014)
Ascorbic Acid and the Brain: Rationale for the Use against Cognitive Decline
Fiona E. Harrison et al.
NUTRIENTS (2014)
Effects of Vitamin E on Cognitive Performance during Ageing and in Alzheimer's Disease
Giorgio La Fata et al.
NUTRIENTS (2014)
Supplemental Substances Derived from Foods as Adjunctive Therapeutic Agents for Treatment of Neurodegenerative Diseases and Disorders
Gregory E. Bigford et al.
ADVANCES IN NUTRITION (2014)
Resveratrol as a Therapeutic Agent for Alzheimer's Disease
Teng Ma et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Protein Tyrosine Nitration: Biochemical Mechanisms and Structural Basis of Functional Effects
Rafael Radi
ACCOUNTS OF CHEMICAL RESEARCH (2013)
Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model
Hyunjin Vincent Kim et al.
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS (2013)
The Cystine/Glutamate Antiporter System xc- in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
Jan Lewerenz et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
The Gasotransmitter Hydrogen Sulfide Induces Nrf2-Target Genes by Inactivating the Keap1 Ubiquitin Ligase Substrate Adaptor Through Formation of a Disulfide Bond Between Cys-226 and Cys-613
John M. Hourihan et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease
Maria E. Solesio et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
The NOX1/4 Inhibitor GKT136901 as Selective and Direct Scavenger of Peroxynitrite
S. Schildknecht et al.
CURRENT MEDICINAL CHEMISTRY (2013)
Sulforaphane ameliorates the development of experimental autoimmune encephalomyelitis by antagonizing oxidative stress and Th17-related inflammation in mice
Bin Li et al.
EXPERIMENTAL NEUROLOGY (2013)
Regulation of system xc - in the SOD1-G93A mouse model of ALS
Rebecca Albano et al.
EXPERIMENTAL NEUROLOGY (2013)
Rosmarinus officinalis L. leaf extract improves memory impairment and affects acetylcholinesterase and butyrylcholinesterase activities in rat brain
Marcin Ozarowski et al.
FITOTERAPIA (2013)
Glutathione metabolism and Parkinson's disease
Michelle Smeyne et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
N-Acetylcysteine amide: a derivative to fulfill the promises of N-Acetylcysteine
K. Sunitha et al.
FREE RADICAL RESEARCH (2013)
NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation
Gregory J. Gatto et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2013)
The NADPH Oxidase Pathway Is Dysregulated by the P2X7 Receptor in the SOD1-G93A Microglia Model of Amyotrophic Lateral Sclerosis
Savina Apolloni et al.
JOURNAL OF IMMUNOLOGY (2013)
Keap1 Is Localized in Neuronal and Glial Cytoplasmic Inclusions in Various Neurodegenerative Diseases
Kunikazu Tanji et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2013)
The Keap1-Nrf2 System Prevents Onset of Diabetes Mellitus
Akira Uruno et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Anti-Inflammatory Dimethylfumarate: A Potential New Therapy for Asthma?
Petra Seidel et al.
MEDIATORS OF INFLAMMATION (2013)
Toxicity of extracellular secreted alpha-synuclein: Its role in nitrosative stress and neurodegeneration
Anna Wilkaniec et al.
NEUROCHEMISTRY INTERNATIONAL (2013)
Diapocynin prevents early Parkinson's disease symptoms in the leucine-rich repeat kinase 2 (LRRK2R1441G) transgenic mouse
Brian P. Dranka et al.
NEUROSCIENCE LETTERS (2013)
Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells
Pengfei Meng et al.
NEUROSCIENCE RESEARCH (2013)
Attenuation of beta-Amyloid- Induced Oxidative Cell Death by Sulforaphane via Activation of NF-E2-Related Factor 2
Chan Lee et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
NADPH Oxidase and the Degeneration of Dopaminergic Neurons in Parkinsonian Mice
Marina S. Hernandes et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Genomic Structure and Variation of Nuclear Factor (Erythroid-Derived 2)-Like 2
Hye-Youn Cho
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Nrf2 participates in depressive disorders through an anti-inflammatory mechanism
Maria Dolores Martin-de-Saavedra et al.
PSYCHONEUROENDOCRINOLOGY (2013)
Complex I deficiencies in neurological disorders
Sergio Papa et al.
TRENDS IN MOLECULAR MEDICINE (2013)
The transsulfuration pathway: a source of cysteine for glutathione in astrocytes
Gethin J. McBean
AMINO ACIDS (2012)
NADPH Oxidase 1-Mediated Oxidative Stress Leads to Dopamine Neuron Death in Parkinson's Disease
Dong-Hee Choi et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Targeting NOX enzymes in the central nervous system: therapeutic opportunities
Silvia Sorce et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTS
Eugenia Cifuentes-Pagano et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Sulfasalazine for brain cancer fits
Harald Sontheimer et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2012)
Off-target thiol alkylation by the NADPH oxidase inhibitor 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine (VAS2870)
Qi-An Sun et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Nicotinamide Adenine Dinucleotide Phosphate Oxidase in Experimental Liver Fibrosis: GKT137831 as a Novel Potential Therapeutic Agent
Tomonori Aoyama et al.
HEPATOLOGY (2012)
Fine Tuning the Reactivity of Corrole-Based Catalytic Antioxidants
Zoya Okun et al.
INORGANIC CHEMISTRY (2012)
Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation
Brian P. Dranka et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Differential regulation of CD4+ T helper cell responses by curcumin in experimental autoimmune encephalomyelitis
Saravanan Kanakasabai et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2012)
Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease
Jaewon Chang et al.
NEUROBIOLOGY OF AGING (2012)
Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice
Kari A. Trumbull et al.
NEUROBIOLOGY OF DISEASE (2012)
Recent Advances in the Treatment of Neurodegenerative Diseases Based on GSH Delivery Systems
Ivana Cacciatore et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Pleiotropic Protective Effects of Phytochemicals in Alzheimer's Disease
Sergio Davinelli et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
A Chemical Analog of Curcumin as an Improved Inhibitor of Amyloid Abeta Oligomerization
Robert A. Orlando et al.
PLOS ONE (2012)
Identification of Novel microRNAs in Post-Transcriptional Control of Nrf2 Expression and Redox Homeostasis in Neuronal, SH-SY5Y Cells
Madhusudhanan Narasimhan et al.
PLOS ONE (2012)
Acetyl-L-carnitine and alpha-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy
Sawsan A. Zaitone et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2012)
Dysregulation of Glutathione Homeostasis in Neurodegenerative Diseases
William M. Johnson et al.
NUTRIENTS (2012)
Thinking Outside the Cleft to Understand Synaptic Activity: Contribution of the Cystine-Glutamate Antiporter (System xc-) to Normal and Pathological Glutamatergic Signaling
Richard Bridges et al.
PHARMACOLOGICAL REVIEWS (2012)
Pharmacological Targeting of the Transcription Factor Nrf2 at the Basal Ganglia Provides Disease Modifying Therapy for Experimental Parkinsonism
Agnieszka Jazwa et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Activation of Nuclear Factor Erythroid 2-Related Factor 2 Cytoprotective Signaling by Curcumin Protect Primary Spinal Cord Astrocytes against Oxidative Toxicity
Hong Jiang et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)
Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors
Francesca Gaggini et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
Ralf A. Linker et al.
BRAIN (2011)
NADPH oxidase inhibitors: a patent review
Jung-Ae Kim et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2011)
Dopaminergic neurons of system xc--deficient mice are highly protected against 6-hydroxydopamine-induced toxicity
Ann Massie et al.
FASEB JOURNAL (2011)
Curcumin and its nano-formulation: The kinetics of tissue distribution and blood-brain barrier penetration
Yin-Meng Tsai et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2011)
Increased expression of cystine/glutamate antiporter in multiple sclerosis
Olatz Pampliega et al.
JOURNAL OF NEUROINFLAMMATION (2011)
The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease
Meagan J. McManus et al.
JOURNAL OF NEUROSCIENCE (2011)
Peroxiredoxin-2 Protects against 6-Hydroxydopamine-Induced Dopaminergic Neurodegeneration via Attenuation of the Apoptosis Signal-Regulating Kinase (ASK1) Signaling Cascade
Xiaoming Hu et al.
JOURNAL OF NEUROSCIENCE (2011)
Beneficial Role of Nrf2 in Regulating NADPH Generation and Consumption
Kai Connie Wu et al.
TOXICOLOGICAL SCIENCES (2011)
A Novel and Specific NADPH Oxidase-1 (Nox1) Small-Molecule Inhibitor Blocks the Formation of Functional Invadopodia in Human Colon Cancer Cells
Davide Gianni et al.
ACS CHEMICAL BIOLOGY (2010)
Neuroprotective Effects of Zonisamide Target Astrocyte
Masato Asanuma et al.
ANNALS OF NEUROLOGY (2010)
Comparative pharmacology of chemically distinct NADPH oxidase inhibitors
S. Wind et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals
Jesus Aguirre et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions
Jack van Horssen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
Benoit Laleu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Metallocorroles as cytoprotective agents against oxidative and nitrative stress in cellular models of neurodegeneration
Lana Kupershmidt et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Liposomal-Glutathione Provides Maintenance of Intracellular Glutathione and Neuroprotection in Mesencephalic Neuronal Cells
Gail D. Zeevalk et al.
NEUROCHEMICAL RESEARCH (2010)
Glutathione depletion causes a JNK and p38MAPK-mediated increase in expression of cystathionine-γ-lyase and upregulation of the transsulfuration pathway in C6 glioma cells
Sarah Kandil et al.
NEUROCHEMISTRY INTERNATIONAL (2010)
The Absence of the Pro-antioxidant Transcription Factor Nrf2 Exacerbates Experimental Autoimmune Encephalomyelitis
Delinda A. Johnson et al.
TOXICOLOGICAL SCIENCES (2010)
NOX Enzymes in the Central Nervous System: From Signaling to Disease
Silvia Sorce et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice
Melinda S. Yates et al.
CARCINOGENESIS (2009)
Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production
Lin Xie et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2009)
Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease
Magali Dumont et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Acetylation of Nrf2 by p300/CBP Augments Promoter-Specific DNA Binding of Nrf2 during the Antioxidant Response
Zheng Sun et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Classical Inhibitors of NOX NAD(P) H Oxidases Are Not Specific
Elisabetta Aldieri et al.
CURRENT DRUG METABOLISM (2008)
Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression
J. van Horssen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant
Sabine Heumueller et al.
HYPERTENSION (2008)
Cellular and Behavioral Effects of Stilbene Resveratrol Analogues: Implications for Reducing the Deleterious Effects of Aging
James A. Joseph et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)
The transcription factor Nrf2 is a therapeutic target against brain inflammation
Nadia G. Innamorato et al.
JOURNAL OF IMMUNOLOGY (2008)
GSK-3β down-regulates the transcription factor Nrf2 after oxidant damage:: relevance to exposure of neuronal cells to oxidative stress
Ana I. Rojo et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1
Takumi Satoh et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Nuclear Erythroid 2-Related Factor 2-Antioxidative Response Element Signaling Pathway in Motor Cortex and Spinal Cord in Amyotrophic Lateral Sclerosis
Alexander Sarlette et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
Nuclear factor erythroid 2-related factor 2 protects against beta amyloid
Katja Kanninen et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Correlation between DJ-1 levels in the cerebrospinal fluid and the progression of disabilities in multiple sclerosis patients
M. Hirotani et al.
MULTIPLE SCLEROSIS JOURNAL (2008)
Beneficial effects of carnosic acid on dieldrin-induced dopaminergic neuronal cell death
Jeong Ae Park et al.
NEUROREPORT (2008)
Bioavailability of curcumin: Problems and promises
Preetha Anand et al.
MOLECULAR PHARMACEUTICS (2007)
N-Acetylcysteine -: a safe antidote for cysteine/glutathione deficiency
Kondala R. Atkuri et al.
CURRENT OPINION IN PHARMACOLOGY (2007)
Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model
M. Garcia-Alloza et al.
JOURNAL OF NEUROCHEMISTRY (2007)
GSK-3β acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2
Abhinav K. Jain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: Relevance to Parkinson's disease
G. D. Zeevalk et al.
EXPERIMENTAL NEUROLOGY (2007)
Expression of Nrf2 in neurodegenerative diseases
Chenere P. Ramsey et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
A functional transsulfuration pathway in the brain links to glutathione homeostasis
Victor Vitvitsky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Curry consumption and cognitive function in the elderly
Tze-Pin Ng et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2006)
Nitroxidative, nitrosative, and nitrative stress: Kinetic predictions of reactive nitrogen species chemistry under biological conditions
Jack R. Lancaster
CHEMICAL RESEARCH IN TOXICOLOGY (2006)
Mechanism of action of sulforaphane: Inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells
Young-Sam Keum et al.
CANCER RESEARCH (2006)
Involvement of glutaredoxin-1 and thioredoxin-1 in β-amyloid toxicity and Alzheimer's disease
S. Akterin et al.
CELL DEATH AND DIFFERENTIATION (2006)
Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation
Henrik ten Freyhaus et al.
CARDIOVASCULAR RESEARCH (2006)
Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration
S. Schilling et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2006)
Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2
Qiang Ma et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
System xc- and apolipoprotein e expressed by microglia have opposite effects on the neurotoxicity of amyloid-β peptide 1-40
S Qin et al.
JOURNAL OF NEUROSCIENCE (2006)
Say NO to neurodegeneration: Role of S-nitrosylation in neurodegenerative disorders
Kenny K. K. Chung
NEUROSIGNALS (2006)
NADPH oxidases of the brain: Distribution, regulation, and function
David W. Infanger et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo
FS Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Complexity of Astrocyte-Motor Neuron Interactions in Amyotrophic Lateral Sclerosis
Mariana Pehar et al.
NEURODEGENERATIVE DISEASES (2005)
Curcumin has potent anti-amyloidogenic effects for Alzheimer's β-amyloid fibrils in vitro
K Ono et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate for proteasomal degradation of Nrf2
A Kobayashi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
SB Cullinan et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Curcurnin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
E Balogun et al.
BIOCHEMICAL JOURNAL (2003)
Red wine ingredient resveratrol protects from beta-amyloid neurotoxicity
E Savaskan et al.
GERONTOLOGY (2003)
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
HC Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the xc- cystine transporter:: a new action for an old drug
PW Gout et al.
LEUKEMIA (2001)
Incidence of Alzheimer's disease in a rural community in India - The Indo-US Study
V Chandra et al.
NEUROLOGY (2001)
Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O2- and systolic blood pressure in mice
FE Rey et al.
CIRCULATION RESEARCH (2001)
Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase 1 gene
S Dhakshinamoorthy et al.
ONCOGENE (2001)
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
T Ishii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
