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Low expression of the β-ENaC subunit impairs lung fluid clearance in the mouse
Nadia Randrianarison et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Preventive but Not Late Amiloride Therapy Reduces Morbidity and Mortality of Lung Disease in βENaC-overexpressing Mice
Zhe Zhou et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)
ASIC3, a sensor of acidic and primary inflammatory pain
Emmanuel Deval et al.
EMBO JOURNAL (2008)
Regulation of ASIC activity by ASIC4 - new insights into ASIC channel function revealed by a yeast two-hybrid assay
Emmanuelle Donier et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Sensing tension - Epithelial sodium channel/acid-sensing ion channel proteins in cardiovascular homeostasis
Heather A. Drummond et al.
HYPERTENSION (2008)
Plasmin Activates Epithelial Na+ Channels by Cleaving the γ Subunit
Christopher J. Passero et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Preferential assembly of epithelial sodium channel (ENaC) subunits in Xenopus Oocytes -: Role of furin-mediated endogenous proteolysis
Michael Harris et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Proteolytic processing of the epithelial sodium channel γ subunit has a dominant role in channel activation
Marcelo D. Carattino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
ENaC Proteolytic Regulation by Channel-activating Protease 2
Agustin Garcia-Caballero et al.
JOURNAL OF GENERAL PHYSIOLOGY (2008)
Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1
Alan R. Light et al.
JOURNAL OF NEUROPHYSIOLOGY (2008)
Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N′-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease
Andrew J. Hirsh et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome
Marko Bertog et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone
Motoko Chiga et al.
KIDNEY INTERNATIONAL (2008)
Acid-sensing ion channels interact with and inhibit BKK+ channels
Elena Yerimolaieva Petroff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Epithelial Na+ channel activation and processing in mice lacking SGK1
Geza Fejes-Toth et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Defective ENaC processing and function in tissue kallikrein-deficient mice
Nicolas Picard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Postnatal requirement of the epithelial sodium channel for maintenance of epidermal barrier function
Roch-Philippe Charles et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Modulation of acid-sensing ion channel activity by nitric oxide
Herve Cadiou et al.
JOURNAL OF NEUROSCIENCE (2007)
Dual effect of acid pH on purinergic P2X3 receptors depends on the histidine 206 residue
Zoltan Gerevich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Nafamostat mesilate reversibly blocks acid-sensing ion channel currents
Shinya Ugawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH
Jayasankar Jasti et al.
NATURE (2007)
A tarantula peptide against pain via ASIC1a channels and opioid mechanisms
Michel Mazzuca et al.
NATURE NEUROSCIENCE (2007)
Modulation of extracellular proton fluxes from retinal horizontal cells of the catfish by depolarization and glutamate
Matthew A. Kreitzer et al.
JOURNAL OF GENERAL PHYSIOLOGY (2007)
β-Liddle mutation of the epithelial sodium channel increases alveolar fluid clearance and reduces the severity of hydrostatic pulmonary oedema in mice
Nadia Randrianarison et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Determination of epithelial Na+ channel subunit stoichiometry from single-channel conductances
Arun Anantharam et al.
JOURNAL OF GENERAL PHYSIOLOGY (2007)
Arachidonic acid potentiates acid-sensing ion channels in rat sensory neurons by a direct action
E. S. Smith et al.
NEUROSCIENCE (2007)
Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the γ-subunit
James B. Bruns et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia
Patrick A. Hughes et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2007)
A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes
Michael Harris et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Rapid responses to steroid hormones in the kidney
Warren Thomas et al.
NEPHRON PHYSIOLOGY (2007)
Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption
Natalia Makhanova et al.
HYPERTENSION (2006)
The connecting tubule is the main site of the furosemide-induced urinary acidification by the vacuolar H+-ATPase
J. Kovacikova et al.
KIDNEY INTERNATIONAL (2006)
Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines
Xiang-ming Zha et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Acid-sensing ion channels: advances, questions and therapeutic opportunities
John A. Wemmie et al.
TRENDS IN NEUROSCIENCES (2006)
Inhibition of prostasin-induced ENaC activities by PN-1 and regulation of PN-1 expression by TGF-β1 and aldosterone
N. Wakida et al.
KIDNEY INTERNATIONAL (2006)
Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury
Olivier Poirot et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Attenuation of experimental arthritis in TRPV1R knockout mice
N. J. Barton et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2006)
Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia
Junichi Yagi et al.
CIRCULATION RESEARCH (2006)
Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: Drugs for cystic fibrosis and chronic bronchitis
Andrew J. Hirsh et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
TREK-2 (K2P10.1) and TRESK (K2P18.1) are major background K+ channels in dorsal root ganglion neurons
Dawon Kang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition
S Sheng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
FMRFamide-gated sodium channel and ASIC channels: A new class of ionotropic receptors for FMRFamide and related peptides
Eric Lingueglia et al.
PEPTIDES (2006)
Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1
Ditte Andreasen et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
The V-type H+ ATPase:: molecular structure and function, physiological roles and regulation
KW Beyenbach et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2006)
The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a
M Salinas et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating
M Vukicevic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death
J Gao et al.
NEURON (2005)
A direct relationship between plasma aldosterone and cardiac L-type Ca2+ current in mice
R Perrier et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Central role for ENaC in development of hypertension
JH Pratt
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli
JS Mogil et al.
JOURNAL OF NEUROSCIENCE (2005)
Involvement of transient receptor potential vanilloid 1 in the vascular and hyperalgesic components of joint inflammation
J Keeble et al.
ARTHRITIS AND RHEUMATISM (2005)
Electrophysiological and in vivo characterization of A-317567, a novel blocker of acid sensing ion channels
GR Dubé et al.
PAIN (2005)
Improvement in blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension
C Saha et al.
HYPERTENSION (2005)
Proton modulation of recombinant GABAA receptors:: influence of GABA concentration and the β subunit TM2-TM3 domain
ME Wilkins et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantoic placenta
H Tanaka et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats
P Honore et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Epithelial Na+ channel subunit stoichiometry
A Staruschenko et al.
BIOPHYSICAL JOURNAL (2005)
Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport
RA Caldwell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)
Proton-mediated feedback inhibition of presynaptic calcium channels at the cone photoreceptor synapse
JP Vessey et al.
JOURNAL OF NEUROSCIENCE (2005)
Aldosterone biosynthesis, regulation, and classical mechanism of action
G Williams
HEART FAILURE REVIEWS (2005)
Vasopressin-stimulated CFTR Cl- currents are increased in the renal collecting duct cells of a mouse model of Liddle's syndrome
CT Chang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Acid-sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones
LJ Drew et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Epithelial sodium channels are activated by furin-dependent proteolysis
RP Hughey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Regulation of prostasin expression and function in the prostate
LM Chen et al.
PROSTATE (2004)
Protons activate the δ-subunit of the epithelial Na+ channel in humans
H Yamamura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
pH dependency and desensitization kinetics of heterologously expressed combinations of acid-sensing ion channel subunits
M Hesselager et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Background potassium channel block and TRPV1 activation contribute to proton depolarization of sensory neurons from humans with neuropathic pain
TK Baumann et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Hepatocyte growth factor activator inhibitor types 1 and 2 are expressed by tubular epithelium in kidney and downregulated in renal cell carcinoma
M Yamauchi et al.
JOURNAL OF UROLOGY (2004)
Molecular determinants of proton modulation of glycine receptors
ZL Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Neuroprotection in ischemia: Blocking calcium-permeable acid-sensing ion channels
ZG Xiong et al.
CELL (2004)
Selective regulation of acid-sensing ion channel 1 by serine proteases
O Poirot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Modulatory effects of acid-sensing ion channels on action potential generation in hippocampal neurons
M Vukicevic et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Differential modulation of β2 and β4 subunits of human neuronal nicotinic acetylcholine receptors by acidification
G Abdrakhmanova et al.
MOLECULAR PHARMACOLOGY (2004)
A further subgroup analysis of the effects of the DASH diet and three dietary sodium levels on blood pressure: Results of the DASH-sodium trial
GA Bray et al.
AMERICAN JOURNAL OF CARDIOLOGY (2004)
Acid-induced pain and its modulation in humans
NG Jones et al.
JOURNAL OF NEUROSCIENCE (2004)
Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease
AJ Hirsh et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Degenerin sites mediate proton activation of δβγ-epithelial sodium channel
HL Ji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Characterization and function of twik-related acid sensing K+ channels in a rat nociceptive cell
BY Cooper et al.
NEUROSCIENCE (2004)
Chronic hyperaldosteronism in a transgenic mouse model fails to induce cardiac remodeling and fibrosis under a normal-salt diet
Q Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2004)
Defective respiratory amiloride-sensitive sodium transport predisposes to pulmonary oedema and delays its resolution in mice
M Egli et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Mineralocorticoid receptor antagonists do not block rapid ERK activation by aldosterone
K Rossol-Haseroth et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
pH-dependent modulation of Kv1.3 inactivation:: role of His399
S Somodi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Identification of the Ca2+ blocking site of acid-sensing ion channel (ASIC) 1:: Implications for channel gating
M Paukert et al.
JOURNAL OF GENERAL PHYSIOLOGY (2004)
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice
M Mall et al.
NATURE MEDICINE (2004)
Regulation and modulation of pH in the brain
M Chesler
PHYSIOLOGICAL REVIEWS (2003)
Maturation of the epithelial Na+ channel involves proteolytic processing of the α- and γ-subunits
RP Hughey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Dysfunction of the epithelial sodium channel expressed in the kidney of a mouse model for Liddle syndrome
S Pradervand et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Treat high blood pressure sooner: Tougher, simpler JNC 7 guidelines
DG Vidt et al.
CLEVELAND CLINIC JOURNAL OF MEDICINE (2003)
Proton-induced calcitonin gene-related peptide release from rat sciatic nerve axons, in vitro, involving TRPV1
MJM Fischer et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Mineralocorticoid regulation of epithelial Na+ channels is maintained in a mouse model of Liddle's syndrome
A Dahlmann et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2003)
Acidosis decreases low Ca2+-induced neuronal excitation by inhibiting the activity of calcium-sensing cation channels in cultured mouse hippocampal neurons
XP Chu et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Impaired pressure sensation in mice lacking TRPV4
M Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability
E Deval et al.
NEUROPHARMACOLOGY (2003)
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade
DC Immke et al.
NEURON (2003)
Mechanisms underlying modulation of neuronal KCNQ2/KCNQ3 potassium channels by extracellular protons
DL Prole et al.
JOURNAL OF GENERAL PHYSIOLOGY (2003)
Differential response properties of IB4-positive and -negative unmyelinated sensory neurons to protons and capsaicin
S Dirajlal et al.
JOURNAL OF NEUROPHYSIOLOGY (2003)
Correlation of local changes in extracellular oxygen and pH that accompany dopaminergic terminal activity in the rat caudate-putamen
BJ Venton et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Lung edema clearance:: 20 years of progress selected contribution:: Limiting Na+ transport rate in airway epithelia from α-ENaC transgenic mice:: a model for pulmonary edema
R Olivier et al.
JOURNAL OF APPLIED PHYSIOLOGY (2002)
Alternative splicing and interaction with di- and polyvalent cations control the dynamic range of acid-sensing ion channel 1 (ASIC1)
E Babini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro
M Guipponi et al.
HUMAN MOLECULAR GENETICS (2002)
Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals
NJ Allen et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
Na self inhibition of human epithelial Na channel:: Temperature dependence and effect of extracellular proteases
A Chraïbi et al.
JOURNAL OF GENERAL PHYSIOLOGY (2002)
Molecular determinants of the inhibition of human Kv1.5 potassium currents by external protons and Zn2+
SJ Kehl et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory
JA Wemmie et al.
NEURON (2002)
The ENaC channel is required for normal epidermal differentiation
T Mauro et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2002)
Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons
CJ Benson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Protons enhance the gating kinetics of the α3/β4 neuronal nicotinic acetylcholine receptor by increasing its apparent affinity to agonists
G Abdrakhmanova et al.
MOLECULAR PHARMACOLOGY (2002)
A role for CO2 and bicarbonate transporters in metabolic exchanges in the brain
JW Deitmer
JOURNAL OF NEUROCHEMISTRY (2002)
Exocytosed protons feedback to suppress the Ca2+ current in mammalian cone photoreceptors
SH DeVries
NEURON (2001)
Effects of diet and sodium intake on blood pressure: Subgroup analysis of the DASH-Sodium Trial
WM Vollmer et al.
ANNALS OF INTERNAL MEDICINE (2001)
Regulation of the abundance of renal sodium transporters and channels by vasopressin
CA Ecelbarger et al.
EXPERIMENTAL NEUROLOGY (2001)
Molecular and functional characterization of acid-sensing ion channel (ASIC) 1b
EL Bässler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Functional analysis of secreted and transmembrane proteins critical to mouse development
KJ Mitchell et al.
NATURE GENETICS (2001)
Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice
DA Cockayne et al.
NATURE (2000)
Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors
V Souslova et al.
NATURE (2000)
Inhibition of the K+ channel Kv1.4 by acidosis:: protonation of an extracellular histidine slows the recovery from N-type inactivation
TW Claydon et al.
JOURNAL OF PHYSIOLOGY-LONDON (2000)
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
MJ Caterina et al.
SCIENCE (2000)
Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels
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