Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/ijms21030950
Keywords
riboflavin; vitamin B2; complementary medicine; functional food; oxidative stress; cancer; neurodegeneration; muscular degeneration
Funding
- Horizon 2020-MSCA-RISE 2018, Oxigenated [823879]
- University of Phayao, Thailand
- German Research Foundation (DFG)
- Charite-Universitatsmedizin Berlin
- Hans-Joachim Hoster Foundation
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Riboflavin (RF) is a water-soluble member of the B-vitamin family. Sufficient dietary and supplemental RF intake appears to have a protective effect on various medical conditions such as sepsis, ischemia etc., while it also contributes to the reduction in the risk of some forms of cancer in humans. These biological effects of RF have been widely studied for their anti-oxidant, anti-aging, anti-inflammatory, anti-nociceptive and anti-cancer properties. Moreover, the combination of RF and other compounds or drugs can have a wide variety of effects and protective properties, and diminish the toxic effect of drugs in several treatments. Research has been done in order to review the latest findings about the link between RF and different clinical aberrations. Since further studies have been published in this field, it is appropriate to consider a re-evaluation of the importance of RF in terms of its beneficial properties.
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