Related references
Note: Only part of the references are listed.Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer's disease
Darshpreet Kaur et al.
INFLAMMOPHARMACOLOGY (2019)
Synapse loss and progress of Alzheimer's disease - A network model
G. Kashyap et al.
SCIENTIFIC REPORTS (2019)
β-amyloid pathology and hippocampal atrophy are independently associated with memory function in cognitively healthy elderly
Anna L. Svenningsson et al.
SCIENTIFIC REPORTS (2019)
Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer's Disease
Rotem Volkman et al.
FRONTIERS IN NEUROSCIENCE (2019)
Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer's disease
Dong Kyu Kim et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2019)
History and progress of hypotheses and clinical trials for Alzheimer's disease
Pei-Pei Liu et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2019)
Motor function deficits in the 12 month-old female 5xFAD mouse model of Alzheimer's disease
T. P. O'Leary et al.
BEHAVIOURAL BRAIN RESEARCH (2018)
Microglia and Astrocytes in Alzheimer's Disease: Implications for Therapy
Marc Fakhoury
CURRENT NEUROPHARMACOLOGY (2018)
Differences Between Women and Men in Incidence Rates of Dementia and Alzheimer's Disease
Christopher R. Beam et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Amyloid-β Plaques in Clinical Alzheimer's Disease Brain Incorporate Stable Isotope Tracer In Vivo and Exhibit Nanoscale Heterogeneity
Norelle C. Wildburger et al.
FRONTIERS IN NEUROLOGY (2018)
THE AMYLOID HYPOTHESIS ON TRAIL
Simon Makin
NATURE (2018)
Constitutive ablation of caspase-6 reduces the inflammatory response and behavioural changes caused by peripheral pro-inflammatory stimuli
Safia Ladha et al.
CELL DEATH DISCOVERY (2018)
Female-specific effect of the BDNF gene on Alzheimer's disease
Guo-Dong Li et al.
NEUROBIOLOGY OF AGING (2017)
Alzheimer's Disease and the Amyloid-β Peptide
M. Paul Murphy et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Caspase-6 mediates resistance against Burkholderia pseudomallei infection and influences the expression of detrimental cytokines
Alexander Bartel et al.
PLOS ONE (2017)
Amyloid beta: structure, biology and structure-based therapeutic development
Guo-fang Chen et al.
ACTA PHARMACOLOGICA SINICA (2017)
Impact of Cytokines and Chemokines on Alzheimer's Disease Neuropathological Hallmarks
Catarina Domingues et al.
CURRENT ALZHEIMER RESEARCH (2017)
Balancing the immune response in the brain: IL-10 and its regulation
Diogo Lobo-Silva et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Spatial learning and memory impairments are associated with increased neuronal activity in 5XFAD mouse as measured by manganese-enhanced magnetic resonance imaging
Xiang Tang et al.
ONCOTARGET (2016)
Activation and Regulation of Caspase-6 and Its Role in Neurodegenerative Diseases
Xiao-Jun Wang et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 55 (2015)
Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation
V. Kaushal et al.
CELL DEATH AND DIFFERENTIATION (2015)
Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology
Raluca Elena Sandu et al.
NEURAL REGENERATION RESEARCH (2015)
The role of amyloid-beta in the regulation of memory
John E. Morley et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment
A. C. LeBlanc et al.
CELL DEATH AND DIFFERENTIATION (2014)
Abnormal vibrissa-related behavior and loss of barrel field inhibitory neurons in 5xFAD transgenics
T. J. Flanigan et al.
GENES BRAIN AND BEHAVIOR (2014)
Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion
Temugin Berta et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease
Verena Landel et al.
MOLECULAR NEURODEGENERATION (2014)
Behavioral and EEG changes in male 5xFAD mice
F. Schneider et al.
PHYSIOLOGY & BEHAVIOR (2014)
Galantamine Slows Down Plaque Formation and Behavioral Decline in the 5XFAD Mouse Model of Alzheimer's Disease
Soumee Bhattacharya et al.
PLOS ONE (2014)
IL-6 in Inflammation, Immunity, and Disease
Toshio Tanaka et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
High-dose of vitamin C supplementation reduces amyloid plaque burden and ameliorates pathological changes in the brain of 5XFAD mice
S-Y Kook et al.
CELL DEATH & DISEASE (2014)
Sex-dependent Differences in Intestinal Tumorigenesis Induced in Apc1638N/+ Mice by Exposure to γ Rays
Daniela Trani et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2013)
Alzheimer disease in the United States (2010-2050) estimated using the 2010 census
Liesi E. Hebert et al.
NEUROLOGY (2013)
Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease
B. Parajuli et al.
CELL DEATH & DISEASE (2013)
Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice
Valeria Uribe et al.
HUMAN MOLECULAR GENETICS (2012)
A Caspase Cascade Regulating Developmental Axon Degeneration
David J. Simon et al.
JOURNAL OF NEUROSCIENCE (2012)
No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease
Antje Hillmann et al.
NEUROBIOLOGY OF AGING (2012)
Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal A beta aggregation in the 5XFAD mouse model of Alzheimer's disease
Sadim Jawhar et al.
NEUROBIOLOGY OF AGING (2012)
Neurologic and motor dysfunctions in APP transgenic mice
Robert Lalonde et al.
REVIEWS IN THE NEUROSCIENCES (2012)
A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines
Jose Miguel Rubio-Perez et al.
SCIENTIFIC WORLD JOURNAL (2012)
Understanding the mechanism of IL-1β secretion
Gloria Lopez-Castejon et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2011)
Strain and Sex Differences in Anxiety-Like and Social Behaviors in C57BL/6J and BALB/cJ Mice
Xiao-Lei An et al.
EXPERIMENTAL ANIMALS (2011)
Caspase-6 and neurodegeneration
Rona K. Graham et al.
TRENDS IN NEUROSCIENCES (2011)
Massive gliosis induced by interleukin-6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition
Paramita Chakrabarty et al.
FASEB JOURNAL (2010)
Why Women Have More Alzheimer's Disease Than Men: Gender and Mitochondrial Toxicity of Amyloid-beta Peptide
Jose Vina et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Caspase activation precedes and leads to tangles
Alix de Calignon et al.
NATURE (2010)
Human Caspases: Activation, Specificity, and Regulation
Cristina Pop et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Caspases: evolutionary aspects of their functions in vertebrates
K. Sakamaki et al.
JOURNAL OF FISH BIOLOGY (2009)
Amyloid beta mediates memory formation
Ana Garcia-Osta et al.
LEARNING & MEMORY (2009)
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
Anatoly Nikolaev et al.
NATURE (2009)
Sex Differences in Caspase Activation After Stroke
Fudong Liu et al.
STROKE (2009)
Age-dependent phenotypic characteristics of a triple transgenic mouse model of Alzheimer disease
Susanna Pietropaolo et al.
BEHAVIORAL NEUROSCIENCE (2008)
The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective
Solomon S. Shaftel et al.
JOURNAL OF NEUROINFLAMMATION (2008)
Chronic interleukin-1β expression in mouse brain leads to leukocyte infiltration and neutrophil-independent blood brain barrier permeability without overt neurodegeneration
Solomon S. Shaftel et al.
JOURNAL OF NEUROSCIENCE (2007)
Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry
Zeshan Ahmed et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)
Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations:: Potential factors in amyloid plaque formation
Holly Oakley et al.
JOURNAL OF NEUROSCIENCE (2006)
Tissue-specific expression and regulation of sexually dimorphic genes in mice
Xia Yang et al.
GENOME RESEARCH (2006)
Sex differences in inflammation and inflammatory pain in cyclooxygenase-deficient mice
Naomi L. Chillingworth et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2006)
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin
Rona K. Graham et al.
CELL (2006)
Caspase-1 activation of caspase-6 in human apoptotic neurons
H Guo et al.
CELL DEATH AND DIFFERENTIATION (2006)
Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern
T. Melnikova et al.
NEUROSCIENCE (2006)
Morphological characterization of thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Aβ immunotherapy on their clearance
T Bussière et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Caspase activation increases β-amyloid generation independently of caspase cleavage of the β-amyloid precursor protein (APP)
G Tesco et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Neurons, glia, and plasticity in normal brain aging
CE Finch
NEUROBIOLOGY OF AGING (2003)
Apoptotic threshold is lowered by p53 transactivation of caspase-6
TK MacLachan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology
JH Su et al.
BRAIN RESEARCH (2001)
The immune system and memory consolidation: a role for the cytokine IL-1 beta
CR Pugh et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2001)
Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis
TE Allsopp et al.
CELL DEATH AND DIFFERENTIATION (2000)
A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor
DC Lu et al.
NATURE MEDICINE (2000)